Table 4 IC50 for α-α3, α-αM, and α-αMβ2 for human monocyte-myofibroblast differentiation.

From: Blocking antibodies against integrin-α3, -αM, and -αMβ2 de-differentiate myofibroblasts, and improve lung fibrosis and kidney fibrosis

Treatment—antibody

IC50 (ng/ml)

p value

α-αM (clone ICRF44)

59.71

0.0111

α-αMβ2 (MAC1, clone CBRM1/5)

63.33

0.0019

α-α3 (clone 3F9G4)

78.36

0.0001

Back to article page