Table 5 Characteristics of causes of death in APL patients.

From: Analysis of early death in critically ill patients with acute promyelocytic leukaemia in the HICU

Complication

All (%)

Survivors (%)

Nonsurvivors (%)

P*

Cerebral bleeding

20 (45.45)

5 (25)

15 (75)

 

Site of bleeding

Subarachnoid space

7 (35)

4 (20)

3 (15)

0.013

Basal ganglion

11 (55)

0

11 (55)

Thalamus

1 (5)

1 (5)

0

Multiple sites

1 (5)

0

1 (5)

Sepsis

18 (40.90)

7 (38.88)

11 (61.11)

Site of infection

Pulmonary infection

12 (66.66)

5 (27.77)

7 (38.88)

0.792

BSI

4 (22.22)

1 (5.55)

3 (16.66)

SSTIS

2 (11.11)

1 (5.55)

1 (5.55)

Pathogen

Bacterial infection

6 (33.33)

2 (11.11)

4 (22.22)

0.315

Fungal infection

1 (5.55)

1 (5.55)

0

Virus infection

1 (5.55)

0

1 (5.55)

  1. BSI, bloodstream infection; SSTIS, skin and soft tissue infection. Boldface indicates that p values < 0.05 are considered statistically significant.
  2. *Pearson’s or Fisher’s chi-square test.