Fig. 4 | Scientific Reports

Fig. 4

From: Circular RNA HIPK3 mediates epithelial–mesenchymal transition of retinal pigment epithelial cells by sponging multiple microRNAs

Fig. 4

circHIPK3 regulates RPE-EMT process by sponging multiple microRNAs. (A) Sankey diagram for the ceRNA network analysis of circHIPK3. (B) Luciferase activities of wide-type LUC-circHIPK3 after transfection with different miRNA mimics (n = 3). *P < 0.05 versus miR-NC group. (C) circRNA-miRNA binding sequences predicted by bioinformatics analysis. (D) Luciferase activities of mutant LUC-circHIPK3 after transfection with different miRNA mimics (n = 3). ns = not significant versus miR-NC group.

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