Table 1 Baseline characteristics of recipients and donors.
Variables | No IFTA N = 34 | IFTA N = 75 | P-value |
---|---|---|---|
Recipient characteristics | |||
Mean age, years (SD) | 55.0 (11.2) | 55.9 (8.8) | 0.639 |
Female sex, n (%) | 18 (52.9) | 28 (37.3) | 0.126 |
Body mass index, kg/m2 (SD) | 23.3 (3.3) | 23.9 (4.3) | 0.501 |
Diabetes mellitus, n (%) | 12 (35.3) | 21 (28.0) | 0.443 |
Hypertension, n (%) | 31 (91.2) | 59 (78.7) | 0.111 |
Duration of pre-transplant dialysis, months | 90.48 (0–228) | 93.81 (7–276) | 0.828 |
HLA-A, B, DR mismatch, n (SD) | 3.62 (1.95) | 3.59 (1.78) | 0.935 |
HLA-DR mismatch, n (SD) | 1.15 (0.82) | 1.19 (0.73) | 0.801 |
DSA-positive, n (%) | 3 (8.8) | 8 (10.8) | 1.000 |
Induction regimen | 0.196 | ||
Basiliximab, n (%) | 28 (82.4) | 53 (70.7) | |
Anti-thymocyte globulin, n (%) | 6 (17.6) | 22 (29.3) | |
Calcineurin inhibitor | 0.529 | ||
Tacrolimus, n (%) | 33 (97.1) | 74 (98.7) | |
Cyclosporine, n (%) | 1 (2.9) | 1 (1.3) | |
Anti-metabolite | 0.967 | ||
Mycophenolate mofetil, n (%) | 25 (73.5) | 73 (97.3) | |
Enteric-coated mycophenoate sodium, n (%) | 4 (11.8) | 0 | |
None, n (%) | 5 (14.7) | 2 (2.7) | |
Steroid maintenance, n (%) | 34 (100) | 75 (100) | |
Donor characteristics | |||
Mean age, years (SD) | 53.3 (13.3) | 53.6 (10.8) | 0.913 |
Female sex, n (%) | 11 (30.6) | 25 (32.5) | 0.839 |
Cold ischemia time, hours (SD) | 4.91 (2.83) | 4.42 (1.82) | 0.288 |
Terminal serum creatinine, mg/dL (SD) | 1.49 (1.16) | 2.46 (2.15) | 0.003 |
ECD, n (%) | 8 (23.5) | 28 (37.8) | 0.365 |
KDPI, % (SD) | 64.6 (27.0) | 69.3 (20.7) | 0.381 |
Cause of death, CVA, n (%) | 12 (35.3) | 32 (42.7) | 0.467 |