Table 1 Baseline characteristics of recipients and donors.

From: Multicenter, prospective, observational study for urinary exosomal biomarkers of kidney allograft fibrosis

Variables

No IFTA

N = 34

IFTA

N = 75

P-value

Recipient characteristics

 Mean age, years (SD)

55.0 (11.2)

55.9 (8.8)

0.639

 Female sex, n (%)

18 (52.9)

28 (37.3)

0.126

 Body mass index, kg/m2 (SD)

23.3 (3.3)

23.9 (4.3)

0.501

 Diabetes mellitus, n (%)

12 (35.3)

21 (28.0)

0.443

 Hypertension, n (%)

31 (91.2)

59 (78.7)

0.111

 Duration of pre-transplant dialysis, months

90.48 (0–228)

93.81 (7–276)

0.828

 HLA-A, B, DR mismatch, n (SD)

3.62 (1.95)

3.59 (1.78)

0.935

 HLA-DR mismatch, n (SD)

1.15 (0.82)

1.19 (0.73)

0.801

 DSA-positive, n (%)

3 (8.8)

8 (10.8)

1.000

 Induction regimen

0.196

  Basiliximab, n (%)

28 (82.4)

53 (70.7)

 

  Anti-thymocyte globulin, n (%)

6 (17.6)

22 (29.3)

 

 Calcineurin inhibitor

0.529

  Tacrolimus, n (%)

33 (97.1)

74 (98.7)

 

  Cyclosporine, n (%)

1 (2.9)

1 (1.3)

 

 Anti-metabolite

0.967

  Mycophenolate mofetil, n (%)

25 (73.5)

73 (97.3)

 

  Enteric-coated mycophenoate sodium, n (%)

4 (11.8)

0

 

  None, n (%)

5 (14.7)

2 (2.7)

 

 Steroid maintenance, n (%)

34 (100)

75 (100)

 

Donor characteristics

 Mean age, years (SD)

53.3 (13.3)

53.6 (10.8)

0.913

 Female sex, n (%)

11 (30.6)

25 (32.5)

0.839

 Cold ischemia time, hours (SD)

4.91 (2.83)

4.42 (1.82)

0.288

 Terminal serum creatinine, mg/dL (SD)

1.49 (1.16)

2.46 (2.15)

0.003

 ECD, n (%)

8 (23.5)

28 (37.8)

0.365

 KDPI, % (SD)

64.6 (27.0)

69.3 (20.7)

0.381

 Cause of death, CVA, n (%)

12 (35.3)

32 (42.7)

0.467

  1. FSGS, focal segmental glomerulosclerosis; PCKD, polycystic kidney disease; ECD, expanded criteria donor; KDPI, kidney donor profile index.