Fig. 1 | Scientific Reports

Fig. 1

From: Downregulation of CIAPIN1 regulates the proliferation, migration and glycolysis of breast cancer cells via inhibition of STAT3 pathway

Fig. 1

CIAPIN1 expression was upregulated in breast cancer tissues and serum. (A) Representative image of morphological structure by HE staining and CIAPIN1 expression by immunohistochemistry in breast cancer tissues and adjacent tissue (Magnification 200 ×). (B) RT-qPCR was performed to determine the mRNA levels of CIAPIN1 in breast cancer tissues and adjacent tissue. (C) The protein levels of CIAPIN1 in breast cancer tissues (n = 4) and adjacent normal breast tissues (n = 4) were determined by Western blot. (D) ELISA was carried out to measure the serum concentrations of CIAPIN1 from breast cancer (n = 15) and healthy controls (n = 15). The impact of the low (black line) and high (red line) CIAPIN1 expression on (E) Overall survival (OS) and (F) recurrence-free survival (RFS) curves were calculated from the Kaplan‑Meier Plotter. Data are presented as mean ± SD and Dot plots and analyzed using the Student t-test. ***P < 0. 001 vs. control group. N, adjacent normal breast tissues; T, breast cancer tissues.

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