Fig. 3 | Scientific Reports

Fig. 3

From: Downregulation of CIAPIN1 regulates the proliferation, migration and glycolysis of breast cancer cells via inhibition of STAT3 pathway

Fig. 3

Overexpression of CIAPIN1 in breast cancer cells promotes cell proliferation. MCF7 and MDA-MB-468 cells were transfected with pcDNA3.1-CIAPIN1 or vector, and were cultured for 12, 24 48 and 72 h. (A, B) The cell viability was determined by MTT assay in MCF7 and MDA-MB-468 cells, respectively. (C) 5-ethynyl-20-deoxyuridine (EdU) assay was used to assess cell proliferation of MCF7 and MDA-MB-468 cells at 24 h after transfection. (D) Quantification of EdU-positive cells relative to DAPI-positive cells. Data are presented as mean ± SD in triplicates and analyzed using the Student t-test. ***P < 0.01 vs. control group.

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