Fig. 7

Inhibition of CIAPIN1 enhances cellular ROS production and oxidative stress in breast cancer cells. (A) Representative images of DHE staining of MDA-MB-231 and MDA-MB-453 cells. (B) Quantification of DHE-positive cells relative to DAPI-positive cells. Three oxidative stress indicators were measured in the lysate of MDA-MB-231 and MDA-MB-453 cells using the colourimetric method, including (C) MDA, (D) SOD and (E) CAT. Data represent the average of three independent experiments (mean ± SD), and analyzed using Student t test.. ***P < 0.001 vs. si-NC group.