Table 1 The prediction of UC peptides binding to various major histocompatibility variants.

From: A nonadjuvanted HLA-restricted peptide vaccine induced both T and B cell immunity against SARS-CoV-2 spike protein

 

HLA-A/IC50 (nM)

HLA-B/IC50 (nM)

HLA-C/IC50 (nM)

UC-100

02:01

167.9

15:02

1303.9

03:03

3339.0

02:06

267.6

05:01

46.0

03:01

6711.2

07:01

7398.9

30:01

2420.9

08:02

8397.7

30:02

998.8

12:03

28.9

31:01

5134.2

14:02

148.5

32:01

4139.4

15:02

1053.0

UC-152

02:01

51.4

15:02

1880.3

03:03

7561.5

02:06

79.0

05:01

82.0

03:01

2311.0

07:01

3708.3

30:01

1577.5

08:02

5796.4

30:02

838.4

12:03

28.9

31:01

2821.4

14:02

148.5

32:01

2985.0

15:02

938.5

  1. The predicted binding affinity of peptide to MHC-I was analyzed with SMM on the Immune Epitope Database website (http://www.iedb.org/).