Fig. 3
From: Proteomic profiling of cerebrospinal fluid reveals TKT as a potential biomarker for medulloblastoma
Analysis of canonical pathway enrichment. (A) Canonical pathway enrichment analysis using IPA with DEP data. The orange bar indicates a positive Z score, which is an activated pathway in the MBL group. The blue bar indicates a negative Z score, and an inhibited pathway in the MBL group. Color depth represents the degree of the Z score. The horizontal axis indicates −log10 (p value), and the vertical axis represents enriched canonical pathways; (B) PPI network analysis using the STRING database. Proteins for PPI network analysis were extracted from the following enriched canonical pathways: ‘Glycolysis’ and ‘Synatogenesis Signaling Pathway’. Hub proteins for the activated pathway and inhibited pathway in the MBL group are presented. Color depth and node size are expressed by betweenness centrality values.
