Fig. 2 | Scientific Reports

Fig. 2

From: Effects of the lncRNA NBR2 on the proliferation and autophagy of breast cancer cells under starvation conditions

Fig. 2

Inhibition of the lncRNA NBR2 in breast cancer cells. (A) A colony formation assay was used to evaluate the proliferation of MDA-MB-231 and BT-549 cells after knockdown or overexpression of the lncRNA NBR2. (B) MTT proliferation experiments showed that overexpression of the lncRNA NBR2 limited the proliferation of BT-549 and MDA-MB-231 cells, while silencing lncRNA NBR2 promoted the proliferation of cells. (C) The cell cycle distribution of BT-549 and MDA-MB-231 cells was detected by flow cytometry. (D) The percentage of apoptotic cells was detected by Annexin V/PI double staining. The data are expressed as the mean ± SD of three independent experiments. *P < 0.05, **P < 0.01, ***P < 0.001.

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