Fig. 6 | Scientific Reports

Fig. 6

From: Effects of the lncRNA NBR2 on the proliferation and autophagy of breast cancer cells under starvation conditions

Fig. 6

Effects of the lncRNA NBR2 knockdown on tumorigenic ability and autophagy in vivo. (A) BT-549 cells with low lncRNA NBR2 expression and control cells were subcutaneously inoculated into nude mice. Representative images of isolated tumours showing significant growth. (B) RNA was extracted from tumour tissue, and the expression of the lncRNA NBR2 was analysed by qRT-PCR. (C) The volume and weight of subcutaneously transplanted tumours were measured in nude mice. (D) Protein was extracted from the tumour tissue, and autophagy-related protein expression was detected by western blotting. (E) Representative images of H&E staining and the expression of the autophagy-related index LC3 by immunohistochemistry in subcutaneous tumours. *P < 0.05, **P < 0.01, ***P < 0.001.

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