Fig. 2

Forest plot of stroke-free survival according to subgroups. Incidence rate per 100 patient-years and HRs of intensive blood pressure treatment effect, compared with patients in the standard blood pressure control group. HRs were calculated by adjusting the analysis by adding the interaction term of the BP treatment group and glycemic treatment group (the SPRINT are treated as standard glycemic) to adjust for the influence of factorial design in the ACCORD study. The interaction term of the BP treatment group and each subgroup was also added to the Cox model among the subgroup analyses.