Table 2 HRs for the stroke-free survival across the stroke risk score strata.

From: Association between intensive blood pressure lowering and stroke-free survival among patients with and without Diabetes

 

Intensive

Standard

HR

(95% CI)

P

NNTb

(95% CI)

Risk difference

(95% CI)

N

Event

Incidence rate,

N

Event

Incidence rate,

per 100 person-years

per 100 person-years

Overall

 Total

7040

382

1.51 (1.37, 1.67)

7054

452

1.79 (1.63, 1.96)

0.76 (0.65, 0.89)

0.001

102 (53, 361)

0.98 (0.20, 1.76)

 Framingham stroke scorea

  Q1 (0.37–5.15%)

2281

64

0.80 (0.63, 1.03)

2293

67

0.84 (0.66, 1.07)

0.76 (0.52, 1.11)

0.16

861

0.12 (− 0.85, 1.08)

  Q2 (5.16–12.07%)

2239

102

1.26 (1.04, 1.53)

2335

132

1.56 (1.32, 1.86)

0.87 (0.65, 1.16)

0.35

91

1.10 (− 0.18, 2.37)

  Q3 (12.07–78.94%)

2324

191

2.26 (1.96, 2.60)

2250

230

2.81 (2.47, 3.20)

0.69 (0.56, 0.86)

0.001

50 (25, 232)

2.00 (0.33, 3.68)

  1. aStroke risk score categories based on tertiles of the Framingham stroke risk scores (FSRS). 372 missing values of Framingham Stroke Risk Score (FSRS) because of the missing variables used for FSRS calculation (N = 65) and the exclusion of participants with a history of stroke in ACCORD-BP (N = 307).
  2. b95% CI of the number need to treat (NNT) only reported as treatment effects when statistically significantly different.
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