Table 5 Comparison of muscle composition and strength between individuals born preterm with and without bronchopulmonary dysplasia (BPD).

From: Adults born preterm have lower peripheral skeletal muscle area and strength

 

Mean ± SD

Preterm—No BPD

n = 39

Preterm—BPD

n = 16

Mean difference (95% CI)

P

Adjusted mean difference (95% CI)

P

At rest

 Muscle area, mm2

867 (181)

744 (153)

− 122 (− 226, − 19)

0.021

− 119 (− 235, − 3)

0.044

 Shear wave elastography, m/s

2.4 (0.3)

2.5 (0.5)

0.1 (− 0.1, 0.3)

0.267

0.1 (− 0.0, 0.4)

0.204

Maximal contraction

 Muscle area, mm2

854 (217)

768 (172)

− 85 (− 208, 36)

0.165

− 83 (− 220, 53)

0.226

 Shear wave elastography, m/s

3.0 (1.0)

3.4 (0.9)

0.4 (− 0.2, 1.1)

0.178

0.5 (− 0.1, 1.2)

0.115

 Muscle function

n = 38

n = 16

    

 Handgrip, kg

34.7 (10.1)

35.8 (11.3)

1.0 (− 5.2, 7.3)

0.746

4.8 (− 1.8, 11.4)

0.152

 Leg extensor strength, Nm

92.2 (45.0)

74.3 (30.5)

− 17.8 (− 42.5, 6.8)

0.152

− 9.8 (− 36.4, 16.7)

0.461

  1. Significant values are in bold.
  2. Bronchopulmonary dysplasia (BPD) was defined as oxygen use at 36 weeks postmenstrual age. Data are expressed as mean ± SD. Comparisons between No BPD vs BPD group were done by linear regression and adjusted for birthweight; P values are reported in the table.