Table 3 Cost parameter table (yuan).
From: Clinical strategy study on prenatal screening and diagnostic model for Down syndrome
Screening methods | Point estimate | Lower limit of interval | Upper limit of interval | Confirmation method | Notes |
|---|---|---|---|---|---|
Biochemical screening in the first trimester | 150 | 120 | 180 | ± 20% | |
Combined first- trimester screening | 305 | 244 | 366 | ± 20% | |
Double screening in the second trimester | 150 | 120 | 180 | ± 20% | |
Triple screening in the second trimester | 225 | 180 | 270 | ± 20% | |
NIPS | 2400 | 1920 | 2880 | ± 20% | |
Genetic counseling | 20 | 19 | 22 | RWD | In strategy 1–4, the serological screening results indicate high risk or intermediate risk that requires genetic counseling; In strategy 5, NIPS results indicate high risk suggest genetic counseling |
Induced labour | 6000 | 5000 | 7000 | RWD | (1) Diagnosis of DS and termination of pregnancy; (2) Diagnose other chromosomal abnormalities; (3) Induced abortion with other abnormalities (such as ultrasound abnormalities) |
Amniotic fluid chromosomal examination | 3224 | 2486 | 5024 | RWD | All individuals undergoing amniotic fluid chromosomal examination |
