Fig. 5
From: Dipeptide metabolite, glutamyl-glutamate mediates microbe-host interaction to boost spermatogenesis
Metabolic correlation network of the testis in L. plantarum SNI3 treatment compared with control samples. Nodes represent metabolites , with size reflecting the log2 fold change between control and L. plantarum SNI3 treatment in testis samples. Node sizes increase with the log2 fold change , while the criteria for labelling nodes are a log2 fold change cutoff value greater than 0 for upregulation (green color) and less than 0 for downregulation (red color) , respectively. Edges represent shared KEGG pathways. Selected pathways are colored as follows: arachidonic acid metabolism (yellow), linoleic acid metabolism (pink), glycerophospholipid metabolism (blue), fatty acid metabolism (green), protein digestion and amino acid metabolism (orange). Metabolites in green and red squares highlight the most upregulated (Glutamyl glutamate) and the most downregulated metabolite (Phosphatidyl choline , PC(22:6(4Z , 7Z , 10Z , 13Z , 16Z , 19Z)/16:0 , respectively.
