Table 2 Subgroup analyses on VTE risk with PA and sedentary behavior.

From: Role of physical activity and sedentary behavior in venous thromboembolism: a systematic review and dose-response meta-analysis

Characteristics

PA

Sedentary behavior

n

OR (95%CI)

I2

P

n

OR (95%CI)

I2

P

All studies

27

0.83(0.77–0.89)

79.5

< 0.01

7

1.24(1.05–1.47)

73.7

< 0.01

Sex

        

 M/F

7

0.80(0.66–0.97)

79.3

< 0.01

4

1.39(1.06–1.82)

86.6

< 0.01

 F

13

0.81(0.73–0.90)

74.5

< 0.01

2

1.09(0.89–1.32)

0

0.72

 M

7

0.89(0.77–1.03)

73.9

< 0.01

1

1.13(0.83–1.53)

-

-

Age

        

 <60 years

22

0.84(0.78–0.90)

76.3

< 0.01

6

1.15(1.04–1.20)

73.7

0.03

 ≥60 years

5

0.82(0.66–1.01)

83.4

< 0.01

1

2.70(1.81–4.02)

--

--

Location

        

 European

19

0.83(0.77–0.90)

81.90

< 0.01

0

--

--

--

 America

7

0.81(0.68–0.97)

70.80

< 0.01

7

1.24(1.05–1.47)

73.7

< 0.01

 Other

1

1.27(0.49–4.22)

0

0

    

Study type

        

 Cohort

21

0.86(0.80–0.93)

78.3

< 0.01

4

1.16(0.99–1.35)

30.8

0.23

 Case-control

6

0.71(0.64–0.78)

0

0.67

3

1.43(0.95–2.14)

89.2

< 0.01

Cases

        

 <500

11

0.90(0.77–1.06)

69.2

< 0.01

3

1.41(0.89–2.25)

89.4

< 0.01

 ≥ 500

16

0.79(0.72–0.87)

81.9

< 0.01

4

1.16(1.01–1.34)

25.1

0.26

Quality Score

        

 ≤ 7

18

0.84(0.78–0.91)

78.8

< 0.01

4

1.10(1.02–1.19)

0

0.98

 > 7

9

0.79(0.67–0.94)

71.9

< 0.01

3

1.60(0.97–2.63)

89.5

< 0.01

Adjusted for sedentary behavior/PA

        

 No

24

0.84(0.78–0.90)

80.2

< 0.01

3

1.36(0.99–1.87)

89.4

< 0.01

 Yes

3

0.72(0.61–0.85)

0

0.57

4

1.19(1.01–1.39)

17.5

0.30

Adjusted for BMI

        

 No

8

0.80(0.68–0.95)

84.4

< 0.01

2

1.69(0.70–4.06)

94.6

< 0.01

 Yes

19

0.83(0.76–0.91)

77.0

< 0.01

5

1.14(1.02–1.28)

8

0.36

BMI

        

 <26 kg/m2

17

0.81(0.65-1.00)

77.6

< 0.01

2

1.12(0.93–1.36)

0

0.97

 ≥ 26 kg/m2

4

0.65(0.53–0.79)

37.1

0.20

2

1.26(0.87–1.85)

66.3

0.09