Table 1 Comparison of clinical and laboratory variables between survivors and non-survivors with ALF.

From: Application of physiological network mapping in the prediction of survival in critically ill patients with acute liver failure

Variables

Survivors (391)

Mean ± SD/median (IQR)

Non-survivors (249)

Mean ± SD/median (IQR)

p value

Age (years)

57 (43–69)

53 (43–68)

0.38

Male sex, n (%)

204 (52.17)

148 (59.44)

0.072

ICU length of stay (days)

12.19 ± 15.99

7.15 ± 6.30

< 0.001

SOFA

7.05 ± 3.75

8.70 ± 4.04

< 0.001

King’s College criteria (KCC)

1.00 (0.00–1.00)

1.00 (0.00–1.50)

< 0.001

Alanine aminotransferase (U/L)

2082 ± 3187

1344 ± 2031

0.003

Aspartate transaminase (U/L)

2741 ± 4081

2293 ± 3237

0.180

Alkaline phosphatase (U/L)

104 (71–161)

124 (82–178)

0.007

Bilirubin (mg/dL)

2.00 (0.90–5.45)

2.80 (1.00–8.90)

0.016

Albumin (g/dL)

3.04 ± 0.65

2.80 ± 0.54

< 0.001

INR

2.66 ± 2.47

2.83 ± 2.47

0.411

Urea (mg/dL)

37.80 ± 28.94

43.12 ± 27.76

0.022

Creatinine (mg/dL)

2.21 ± 1.83

2.46 ± 1.91

0.093

Sodium (mEq/L)

139.99 ± 5.43

140.10 ± 5.94

0.811

Chloride (mEq/L)

107.28 ± 7.04

106.07 ± 7.29

0.038

Phosphate (mg/dL)

4.37 ± 2.44

5.33 ± 2.24

< 0.001

Bicarbonate (mEq/L)

22.55 ± 4.70

22.36 ± 5.18

0.984

Lactate (mmol/L)

3.10 (1.90–5.55)

5.05 (2.80–8.80)

< 0.001

Arterial blood pH

7.42 ± 0.07

7.39 ± 0.11

0.004

Glucose (mg/dL)

177.36 ± 80.81

202.65 ± 105.80

0.001

Haemoglobin (mg/dL)

11.65 ± 2.15

11.32 ± 2.13

0.058

Platelet count (x 1000/µl)

198 ± 118

180 ± 108

0.061

White blood count (x 1000/µl)

14.31 ± 9.33

14.86 ± 8.10

0.453

Temperature (°C)

36.88 ± 1.22

36.69 ± 1.63

0.089

Heart rate (beat/min)

94 ± 18

95 ± 18

0.522

Mean blood pressure (mmHg)

81.07 ± 12.00

78.02 ± 11.95

0.002

Respiratory rate (breath/min)

20.55 ± 4.97

21.24 ± 4.92

0.084

SpO2 (%)

96.74 ± 2.97

95.84 ± 4.71

0.003

Glasgow coma score (GCS)

9.27 ± 5.11

7.62 ± 4.81

< 0.001

  1. The data are expressed as the mean ± standard deviation or median (interquartile range) depending on the type of variable.
  2. Either t tests or Mann‒Whitney U tests were used for statistical analysis based on the normality of the data.
  3. SOFA sequential organ failure assessment score, INR international normalized ratio, SpO2 oxygen saturation, KCC King’s College Criteria.
  4. Significant values are in bold.
Back to article page