Table 4 Multivariate Cox regression of parenclitic indices vs. SOFA and King’s College Criteria (KCC) in predicting survival in ALF patients admitted to the ICU.

From: Application of physiological network mapping in the prediction of survival in critically ill patients with acute liver failure

Variables

β

SEM

Hazard ratio (95% CI)

p value

δ-pH/bicarbonate

0.275

0.086

1.32 (1.11–1.56)

0.001

SOFA

0.053

0.022

1.06 (1.01–1.10)

0.017

KCC

0.092

0.107

1.10 (0.89–1.35)

0.391

δ-pH/Cr

0.259

0.080

1.30 (1.11–1.52)

0.001

SOFA

0.050

0.023

1.05 (1.01–1.10)

0.027

KCC

0.098

0.107

1.02 (0.82–1.26)

0.362

δ-Lactate/Glu

0.295

0.079

1.34 (1.15–1.57)

< 0.001

SOFA

0.032

0.023

1.03 (0.99–1.08)

0.164

KCC

0.113

0.107

1.10 (0.89–1.36)

0.289

δ-Lactate/HR

0.281

0.078

1.32 (1.14–1.54)

< 0.001

SOFA

0.033

0.023

1.03 (0.99–1.08)

0.159

KCC

0.133

0.106

1.14 (0.93–1.41)

0.211

δ-SpO2/RespR

0.171

0.071

1.19 (1.03–1.36)

0.016

SOFA

0.027

0.021

1.03 (0.99–1.07)

0.188

KCC

0.082

0.098

1.09 (0.9–1.31)

0.402

  1. SOFA sequential organ failure assessment score, Cr serum creatinine, Glu blood glucose, HR heart rate, SEM standard error of the mean, CI confidence interval.
  2. Significant values are in bold.
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