Table 6 Area under the ROC curves, sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and Brier score of parenclitic indices and principal components in combination with the SOFA score compared with the SOFA score alone.

From: Application of physiological network mapping in the prediction of survival in critically ill patients with acute liver failure

Variables

AUC

p-value

Cut-Off

Sensitivity

Specificity

% AUC increase

PPV

NPV

Brier score

SOFA

0.617

< 0.001

6.5

0.683

0.56

–

0.497

0.735

0.1294

δ-pH/Carbonate + SOFA

0.658

< 0.001

0.725

0.606

0.614

6.65

0.5

0.71

0.1268

δ-pH/Creatinine +SOFA

0.633

< 0.001

0.695

0.601

0.592

2.59

0.484

0.7

0.1276

δ-Lactate/HR + SOFA

0.646

< 0.001

0.4954

0.657

0.626

4.7

0.528

0.741

0.1231

δ-Lactate/Glu + SOFA

0.652

< 0.001

0.4902

0.684

0.641

5.67

0.548

0.761

0.1232

δ-SpO2/RespR + SOFA

0.654

< 0.001

0.6461

0.623

0.619

6

0.51

0.721

0.1226

PC-1 + SOFA

0.754

< 0.001

0.6422

0.715

0.714

22.2

0.614

0.797

0.1428

PC-3 + SOFA

0.712

< 0.001

0.5692

0.692

0.667

15.4

0.57

0.773

0.1344

Back to article page