Fig. 2

Reduced spike 1 specific immune responses in allo-HSCT recipients on immunosuppressive treatment. (A) shows serum levels of immunoglobulin G (IgG) against the receptor binding domain (RBD) of spike 1 in patients on immunosuppression (IS) compared to patients not receiving immunosuppression (non-IS). (B) shows interferon-γ (IFN-γ) and (C) shows IL-2 production in plasma supernatant following stimulation of whole blood with spike 1 peptides patients on immunosuppression compared to patients not receiving immunosuppression. Median with 95% confidence interval. Statistical comparisons by Mann-Whitney U-test. P-values are two-sided.