Figure 5
3D structural models of ten BimABptypes and BimABmof Australian strain MSHR668 of Burkholderia pseudomallei. (a) 3D structural model of BimABp type 1 (B. pseudomallei K96243, classified as type 1 was used as the reference strain) as described by Stevens et al.16. The yellow-colored ribbon represents the predicted signal peptide (residues 1–53); green, NIPVPPPMPGGGA direct repeat (residues 63–75); violet, proline-rich motif (residues 78–84); pink, WH and WH2-like domains (residues 155–158); orange, PDASX repeats (residues 244–268); blue, transmembrane domain (residues 458–516). (b – j) 3D structural models of BimABp types 2, 3, 4, 5, 6, 7, 8, 9 and 10. Mutation positions are represented in pink Corey-Pauling-Koltun (CPK) models and labeled accordingly. The red-colored ribbons represent the insertion. (k) 3D structural model of BimABm MSHR668 23. All BimABp and BimABm models were built using I-TASSER. The C-score of the models were: -0.96 for BimABp type 1; -1.16 for type 2; -0.71 for type 3; -0.74 for type 4; -0.99 for type 5; -0.73 for type 6; -1.02 for type 7; -1.12 for type 8; -1.13 for type 9; -0.71 for type 10; and  -0.93 for BimABm MSHR668. Figures were generated by Discovery Studio Visualizer version 21.1.
