Fig. 4 | Scientific Reports

Fig. 4

From: Exploring diagnostic biomarkers of type 2 cardio-renal syndrome based on secreted proteins and bioinformatics analysis

Fig. 4

Functional enrichment analysis and drug screening of the CRS2-related pathogenic genes. (A) Lollipop plot highlighting the results of GO enrichment analysis covering BP, CC, and MF of CRS2-related pathogenic genes. (B) Lollipop plot presenting the KEGG results pertaining to CRS2-related pathogenic genes. (C) Heatmap presenting the top 10 compounds with the most significantly negative enrichment scores as indicated by the cMAP analysis. (D) The description of those top10 compounds. CRS2, Cardio-renal syndrome type 2. GO, gene ontology; BP, biological process; CC, cellular component; MF, molecular function; KEGG, Kyoto Encyclo-pedia of Genes and Genomes; cMAP, connectivity map.

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