Fig. 8
Correlation analysis of 3 hub genes with CKD severity. (A–C) Correlation scatter plots of LOXL1 (A), COL3A1 (B), and CD48 (C) expression with age, respectively. (D–F) Correlation scatter plots of LOXL1 (D), COL3A1 (E), and CD48 (F) expression with gender, respectively. (G–I) Correlation scatter plots of LOXL1 (G), COL3A1 (H), and CD48 (I) expression with gender, respectively. (J–L) Correlation scatter plots of LOXL1 (J), COL3A1 (K), and CD48 (L) expression with gender, respectively. (M,N) ROC curve demonstrating the diagnostic performance of each candidate biomarker and the nomogram model for GFR in GSE137570 dataset cohort1. (O,P) ROC curve demonstrating the diagnostic performance of each candidate biomarker and the nomogram model for TIF in GSE137570 dataset cohort1. CKD, chronic kidney disease; GFR, glomerular filtration rate; TIF, tubulointerstitial fibrosis; ROC, receiver operating characteristic.
