Table 2 Multivariable logistic regression model with HSI-presence on ultra-early DW-MRI scan as the dependent variable.

From: Optimal timing of ultra-early diffusion-weighted MRI in out-of-hospital cardiac arrest patients based on a retrospective multicenter cohort study

Variables

Univariate analysis

Multivariate analysis

OR (95%CI)

P-value

aOR (95%CI)

P-value

Age

1.009 (0.993–10.26)

0.26

  

Male sex

1.313 (0.702–2.455)

0.39

  

CCI score

1.047 (0.923–1.189)

0.47

  

Witness or unwitnessed arrest

 Witnessed arrest

Reference

   

 Unwitnessed arrest

3.095 (1.722–5.563)

< 0.001

  

Bystander CPR or no-bystander CPR

 Bystander CPR

Reference

   

 No-bystander CPR

2.614 (1.374–4.975)

0.003

  

Etiology

 Cardiac etiology

Reference

   

 Non-cardiac etiology

5.940 (2.987–11.812)

< 0.001

  

First monitored rhythm

 

 Shockable rhythm

Reference

   

 Non-shockable rhythm

7.077 (3.447–14.530)

< 0.001

9.974 (3.363–29.578)

< 0.001

 Serum lactic acid level

1.134 (1.065–1.207)

< 0.001

  

 Low-flow time

1.166 (1.119–1.215)

< 0.001

1.176 (1.121–1.233)

< 0.001

 ROSC to DW-MRI scan-interval

1.189 (0.984–1.438)

0.07

1.509 (1.113–2.046)

0.008

  1. Adjusted ORs were obtained by multivariable logistic regression analysis by using the stepwise backward-selection method (Hosmer–Lemeshow test, P = 0.804).
  2. The OR was adjusted for no bystander CPR, non-shockable rhythm, non-cardiac etiology, low-flow time, ROSC to DW-MRI scan-interval, and serum lactic acid.
  3. CCI, Charlson comorbidity index; CPR, cardiopulmonary resuscitation; DW-MRI, diffusion-weighted magnetic resonance imaging; ROSC, return of spontaneous circulation; OR, odds ratio; CI, confidence interval; aOR, adjusted odds ratio.
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