Table 3 Cut-off values of factors influencing HSI-presence in ultra-early DW-MRI.

From: Optimal timing of ultra-early diffusion-weighted MRI in out-of-hospital cardiac arrest patients based on a retrospective multicenter cohort study

 

AUROC (95%CI)

Cut-off value

Sensitivity (95%CI)

Specificity (95%CI)

PPV (95%CI)

NPV (95%CI)

P-value

Low-flow time, min

0.89 (0.83–0.93)

> 21

86 (78–92)

76 (66–84)

80 (71–87)

83 (74–90)

< 0.001

ROSC to DW-MRI scan-interval, h

0.58 (0.51–0.65)

≥ 2.2

72 (63–80)

50 (39–59)

61 (52–69)

62 (50–72)

0.04

First monitored rhythm

0.68 (0.61–0.74)

Non-shockable rhythm

89 (81–94)

47 (37–57)

65 (57–73)

79 (67–89)

< 0.001

  1. HSI, high signal intensity; DW-MRI, diffusion-weighted magnetic resonance imaging; ROSC, return of spontaneous circulation; AUROC, area under the receiver operating characteristic curve; CI, confidence interval; PPV, positive-predictive value; NPV, negative-predictive value; NA, not applicable.