Table 3 Association of FTO variants with Anthropometric parameters according to dominant and non-dominant with non-obese and obese group.
Variables | FTO rs9939609 | FTO rs1421085 | ||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
TT (n = 226) | p value | TA + AA (n = 158) | p value | p value | TT (n = 221) | p value | TC + CC (n = 163) | p value | p value | |||||||
Non-Obese | Obese | Non-Obese | Obese | Between Genotype | Non-Obese | Obese | Non-Obese | Obese | Between Genotype | |||||||
(n = 115) | (n = 111) | (n = 70) | (n = 88) | Non-obese | Obese | (n = 114) | (n = 107) | (n = 71) | (n = 92) | Non-obese | Obese | |||||
Mean ± SD | Mean ± SD | Mean ± SD | Mean ± SD | (n = 185) | (n = 199) | Mean ± SD | Mean ± SD | Mean ± SD | Mean ± SD | (n = 185) | (n = 199) | |||||
Age (years) | 40.16 ± 11.84 | 42.22 ± 11.26 | 0.182 | 39.22 ± 12.32 | 41.80 ± 11.56 | 0.161 | 0.541 | 0.825 | 40.28 ± 11.76 | 42.31 ± 11.21 | 0.201 | 39.05 ± 12.43 | 41.71 ± 11.60 | 0.137 | 0.430 | 0.775 |
Hight (cm) | 159.23 ± 7.25 | 160.06 ± 7.853 | 0.410 | 159.75 ± 7.40 | 159.92 ± 8.98 | 0.659 | 0.544 | 0.429 | 159.19 ± 7.18 | 159.91 ± 7.81 | 0.306 | 159.81 ± 7.50 | 160.09 ± 8.95 | 0.757 | 0.404 | 0.702 |
Weight (kg) | 55.75 ± 6.75 | 76.05 ± 13.98 | 0.000 | 56.53 ± 6.64 | 77.96 ± 18.42 | 0.000 | 0.474 | 0.954 | 55.86 ± 6.69 | 76.15 ± 14.15 | 0.000 | 56.33 ± 6.77 | 77.76 ± 18.10 | 0.000 | 0.676 | 0.965 |
Fat (%) | 27.16 ± 6.12 | 37.34 ± 7.92 | 0.000 | 27.70 ± 5.89 | 38.32 ± 7.98 | 0.000 | 0.553 | 0.542 | 27.24 ± 6.16 | 37.64 ± 7.71 | 0.000 | 27.55 ± 5.84 | 37.94 ± 8.24 | 0.000 | 0.801 | 0.891 |
Fat-mass (kg) | 15.14 ± 4.05 | 28.65 ± 9.89 | 0.000 | 15.60 ± 3.79 | 30.36 ± 12.93 | 0.000 | 0.594 | 0.395 | 15.22 ± 4.05 | 28.92 ± 9.90 | 0.000 | 15.46 ± 3.80 | 29.9612.85 | 0.000 | 0.933 | 0.723 |
Fat-free mass (kg) | 40.52 ± 6.24 | 46.96 ± 8.98 | 0.000 | 40.84 ± 6.54 | 47.50 ± 10.74 | 0.000 | 0.727 | 0.660 | 40.56 ± 6.22 | 46.77 ± 8.86 | 0.000 | 40.78 ± 6.56 | 47.70 ± 10.77 | 0.000 | 0.691 | 0.844 |
Muscle-mass (kg) | 38.27 ± 5.92 | 44.53 ± 8.80 | 0.000 | 38.54 ± 6.24 | 44.79 ± 10.27 | 0.000 | 0.737 | 0.537 | 38.30 ± 5.91 | 44.35 ± 8.70 | 0.000 | 38.48 ± 6.25 | 44.98 ± 10.31 | 0.000 | 0.701 | 0.702 |
Basal Metabolic rate (kcal) | 1182.81 ± 161.38 | 1424.90 ± 247.70 | 0.000 | 1201.23 ± 176.14 | 1449.5 ± 313.38 | 0.000 | 0.525 | 0.846 | 1183.64 ± 161.18 | 1421.27 ± 246.95 | 0.000 | 1199.61 ± 176.39 | 1452.66 ± 311.14 | 0.000 | 0.533 | 0.999 |
Metabolic age (years) | 33.77 ± 9.73 | 55.12 ± 9.94 | 0.000 | 32.94 ± 9.70 | 55.98 ± 11.09 | 0.000 | 0.565 | 0.482 | 34.02 ± 9.60 | 55.58 ± 9.48 | 0.000 | 32.54 ± 9.88 | 55.41 ± 11.52 | 0.000 | 0.317 | 0.859 |
Visceral fat rating | 5.25 ± 2.57 | 10.58 ± 3.70 | 0.000 | 5.08 ± 2.07 | 10.69 ± 4.08 | 0.000 | 0.878 | 0.978 | 5.30 ± 2.54 | 10.61 ± 3.73 | 0.000 | 5 ± 2.12 | 10.65 ± 4.03 | 0.000 | 0.570 | 0.973 |
Body mass index (kg/m2) | 21.97 ± 1.73 | 29.52 ± 4.56 | 0.000 | 22.10 ± 1.60 | 30.30 ± 5.71 | 0.000 | 0.699 | 0.522 | 22.02 ± 1.70 | 29.61 ± 4.62 | 0.000 | 22.01 ± 1.66 | 30.17 ± 5.62 | 0.000 | 0.894 | 0.742 |
Waist circumference (cm) | 76.35 ± 8.36 | 94.18 ± 10.66 | 0.000 | 75.58 ± 11.28 | 94.99 ± 14.17 | 0.000 | 0.846 | 0.813 | 76.55 ± 8.15 | 94.40 ± 10.74 | 0.000 | 75.28 ± 11.69 | 94.70 ± 13.97 | 0.000 | 0.646 | 0.622 |
Hip circumference (cm) | 94.77 ± 4.88 | 107.85 ± 8.24 | 0.000 | 95.25 ± 4.60 | 108.22 ± 11.11 | 0.000 | 0.717 | 0.930 | 94.91 ± 4.78 | 107.96 ± 8.37 | 0.000 | 95.04 ± 4.77 | 108.08 ± 10.89 | 0.000 | 0.921 | 0.799 |
Waist to Hip ratio | 0.80 ± 0.07 | 0.87 ± 0.06 | 0.000 | 0.79 ± 0.11 | 0.87 ± 0.07 | 0.000 | 0.723 | 0.897 | 0.80 ± 0.06 | 0.87 ± 0.06 | 0.000 | 0.79 ± 0.11 | 0.87 ± 0.07 | 0.000 | 0.551 | 0.856 |
Neck circumference (cm) | 32.73 ± 3.55 | 37.14 ± 4.00 | 0.000 | 32.58 ± 2.67 | 37.31 ± 4.16 | 0.000 | 0.915 | 0.943 | 32.83 ± 3.51 | 37.16 ± 4.04 | 0.000 | 32.42 ± 2.73 | 37.28 ± 4.12 | 0.000 | 0.443 | 0.957 |
Middle arm circumference (cm) | 26.41 ± 2.62 | 32.18 ± 3.60 | 0.000 | 26.15 ± 2.34 | 32.25 ± 3.56 | 0.000 | 0.266 | 0.726 | 26.47 ± 2.58 | 32.18 ± 3.66 | 0.000 | 26.06 ± 2.40 | 32.25 ± 3.49 | 0.000 | 0.149 | 0.846 |
Blood Pressure (mmHg) | ||||||||||||||||
Systolic | 118 ± 14.31 | 134.22 ± 18.75 | 0.000 | 121.32 ± 19.70 | 133.55 ± 17.60 | 0.000 | 0.699 | 0.732 | 118.08 ± 14.232 | 133.77 ± 18.41 | 0.000 | 121.14 ± 19.75 | 134.10 ± 18.06 | 0.000 | 0.467 | 0.994 |
Diastolic | 75.55 ± 10.12 | 83.91 ± 11.52 | 0.000 | 75.85 ± 11.28 | 83.79 ± 13.84 | 0.000 | 0.931 | 0.583 | 75.67 ± 10.04 | 83.83 ± 11.51 | 0.000 | 75.66 ± 11.38 | 83.89 ± 13.75 | 0.000 | 0.801 | 0.657 |
