Table 2 PASS analysis of selected compounds against PDK3.
S. No | Compound | Pa | Pi | Activity |
---|---|---|---|---|
1 | Bagrosin | 0.635 | 0.019 | Superoxide dismutase inhibitor |
0.587 | 0.007 | Alzheimer’s disease treatment | ||
0.546 | 0.069 | TP53 expression enhancer | ||
0.531 | 0.041 | Oxygen scavenger | ||
0.518 | 0.034 | Neurotransmitter antagonist | ||
0.498 | 0.001 | JAK2 expression inhibitor | ||
0.301 | 0.089 | Antineoplastic (solid tumors) | ||
2 | Dehydrocholic acid | 0.954 | 0.000 | Bile-salt sulfotransferase inhibitor |
0.904 | 0.004 | Protein-disulfide reductase (glutathione) inhibitor | ||
0.771 | 0.008 | Oxidoreductase inhibitor | ||
0.719 | 0.009 | Analeptic | ||
0.520 | 0.016 | Antimetastatic | ||
0.543 | 0.059 | Antineoplastic |