Table 2 PASS analysis of selected compounds against PDK3.

From: Exploring PDK3 inhibition in lung cancer through drug repurposing for potential therapeutic interventions

S. No

Compound

Pa

Pi

Activity

1

Bagrosin

0.635

0.019

Superoxide dismutase inhibitor

0.587

0.007

Alzheimer’s disease treatment

0.546

0.069

TP53 expression enhancer

0.531

0.041

Oxygen scavenger

0.518

0.034

Neurotransmitter antagonist

0.498

0.001

JAK2 expression inhibitor

0.301

0.089

Antineoplastic (solid tumors)

2

Dehydrocholic acid

0.954

0.000

Bile-salt sulfotransferase inhibitor

0.904

0.004

Protein-disulfide reductase (glutathione) inhibitor

0.771

0.008

Oxidoreductase inhibitor

0.719

0.009

Analeptic

0.520

0.016

Antimetastatic

0.543

0.059

Antineoplastic