Table 1 Factor levels of LAT and sp for 22 factorial design with three center points for nanomicelles.

From: Self-assembled latanoprost loaded soluplus nanomicelles as an ophthalmic drug delivery system for the management of glaucoma

Standard run order

Randomized run order

Amount. of drug (mg)

Coded value of drug

Amount. of Sp (mg)

Coded value of polymer

1

4

1

−1

15

−1

2

2

2

1

15

−1

3

7

1

−1

20

1

4

5

2

1

20

1

5

1

1.5

0

17.5

0

6

3

1.5

0

17.5

0

7

6

1.5

0

17.5

0

  1. LAT − 1 = 1 mg, 1 = 2 mg, Sp -1 = 15 mg and 1 = 20 mg.