Table 2 Factorial design: coded factors of drug and polymer and corresponding responses.

From: Self-assembled latanoprost loaded soluplus nanomicelles as an ophthalmic drug delivery system for the management of glaucoma

Std

Run

Factor A

Drug (mg)

Factor B

Polymer (mg)

Response 1

Particle size (nm)

Response 2

% EE

1

6

−1.00

−1.00

65.4

28.4

2

4

1.00

−1.00

71.15

77.9

3

1

−1.00

1.00

61.19

27.8

4

3

1.00

1.00

66.27

77.2

5

7

0.00

0.00

65.5

53

6

2

0.00

0.00

66.24

53.4

7

5

0.00

0.00

66.24

53