Table 1 Clinicopathologic characteristics of the study patients.
Characteristic | ER+/PR+(n = 10843) | ER+/PR-(n = 1193) | p-Value |
|---|---|---|---|
Age(Mean(range)) | 53.2(16–95) | 56.6(22–87) | 0.000 |
ER+(%, median value) | 90 | 80 | 0.000 |
n(%) | n(%) | ||
Menstrual status | 0.000 | ||
Premenopausal | 5079(47.1) | 320(26.9) | |
Postmenopausal | 5700(52.9) | 869(73.1) | |
Unknown | 64 | 4 | |
T | 0.048 | ||
≤ 2 cm | 6762(62.4) | 709(59.4) | |
> 2 cm | 4081(37.6) | 484(40.6) | |
N | 0.000 | ||
0 | 6814(63.1) | 801(67.1) | |
1 | 2790(25.8) | 243(20.4) | |
2–3 | 1202(11.1) | 149(12.5) | |
Unknown | 37 | 0 | |
HER2 | 0.202 | ||
0 | 3453(31.8) | 402(33.7) | |
1+/2+ | 7390(68.2) | 791(66.3) | |
Ki67 | 0.000 | ||
≤ 20%+ | 6840(63.1) | 619(51.9) | |
> 20%+ | 4003(36.9) | 574(48.1) | |
AR | 0.000 | ||
Positive | 1280(98.5) | 122(93.1) | |
Negative | 19(1.5) | 9(6.9) | |
Unknown | 9544 | 1062 | |
Breast surgery | 0.005 | ||
Lumpectomy | 3669(34.0) | 355(29.9) | |
Mastectomy | 7107(66.0) | 831(70.1) | |
Unknown | 67 | 7 | |
Axillary surgery | 0.062 | ||
SLNB | 4859(46.0) | 497(43.1) | |
ALND | 5705(54.0) | 657(56.9) | |
Unknown | 279 | 39 | |
RT | 0.272 | ||
Yes | 5181(47.8) | 550(46.1) | |
No | 5662(52.2) | 643(53.9) | |
Chemotherapy | 0.000 | ||
Yes | 7289(67.2) | 966(81.0) | |
No | 3554(32.8) | 227(19.0) | |
ET | 0.003 | ||
Yes | 9272(85.5) | 981(82.2) | |
No | 1571(14.5) | 212(17.8) | |
ET regimen | 0.000 | ||
SERM | 3668(40.0) | 264(27.0) | |
SERM + OFS | 269(2.9) | 16(1.6) | |
AI | 4562(49.7) | 668(68.2) | |
AI + OFS | 678(7.4) | 31(3.2) | |
Unknown | 95 | 2 |
