Table 2 Clinicopathologic characteristics of the ET and no-ET ER+/PR- patients.

From: The role of adjuvant endocrine treatment in ER+, PR−, HER2− early breast cancer: a retrospective study of real-world data

Characteristic

ET(n = 981)

no-ET(n = 212)

p-Value

Age(Mean(range))

56.8(22–87)

55.3(30–82)

0.063

ER+(%, median value)

80

50

0.000

 

n(%)

n(%)

 

Menstrual status

  

0.009

Premenopausal

248(25.4)

72(34.1)

 

Postmenopausal

730(74.6)

139(65.9)

 

Unknown

3

1

 

T

  

0.701

≤ 2 cm

578(58.9)

122(57.5)

 

> 2 cm

403(41.1)

90(42.5)

 

N

  

0.942

0

660(67.3)

141(66.5)

 

1

198(20.2)

45(21.2)

 

2–3

123(12.5)

26(12.3)

 

HER2

  

0.000

0

305(31.1)

97(45.8)

 

1+/2+

676(68.9)

115(54.2)

 

Ki67

  

0.023

≤ 20%+

524(53.4)

95(44.8)

 

> 20%+

457(46.6)

117(55.2)

 

Breast surgery

  

0.941

Lumpectomy

292(29.9)

63(30.1)

 

Mastectomy

685(70.1)

146(69.9)

 

Unknown

4

3

 

Axillary surgery

  

0.805

SLNB

415(43.2)

82(42.3)

 

ALND

545(56.8)

112(57.7)

 

Unknown

21

18

 

Post-lumpectomy RT

  

0.000

Yes

253(86.6)

30(47.6)

 

No

39(13.4)

33(52.4)

 

Chemotherapy

  

0.898

Yes

795(81.0)

171(80.7)

 

No

186(19.0)

41(19.3)

 
  1. ET, endocrine treatment; HER2, human epidermal growth factor receptor 2; SLNB, sentinel lymph node biopsy; ALND, axillary lymph node dissection; RT, radiation therapy.