Table 3 Results of 2PN embryo developmental parameters from TLS. TLS: time-lapse system; 2PN: two pronuclei; DC: direct cleavage; RC: reverse cleavage; MN2: multinucleation at the two-cell stage; a vs. a, b vs. b, c vs. c were significantly different.

From: High proportion of zygotes with multiple pronuclei increase the embryo multinucleation rate during conventional IVF

Parameter

Group 1

Group 2

Group 3

P

No. transfers (n)

422

617

156

/

2PN (%,n)

79.17 (3910/4939)a, b

72.54 (5786/7976)a, c

56.05 (1065/1900)b, c

< 0.001

≥ 3PN (%,n)

0 (0/4939)a, b

12.69 (1012/7976)a, c

32.74 (622)b, c

< 0.001

Cleavage (%,n)

98.36 (3846/3910)

98.45 (5696/5786)

98.22 (1046/1065)

0.584

D3 good quality embryos (%,n)

47.76 (1837/3846)

49.17 (2801/5696)

46.37 (485/1046)

0.213

D3 available embryos (%,n)

85.78 (3299/3846)

84.64 (4821/5696)

84.03 (879/1046)

0.382

Blastocyst formation (%)

58.35 (1925/3299)

59.30 (2859/4821)

57.45 (505/879)

0.362

DC (%,n)

26.29 (1011/3846)

25.09 (1429/5696)

23.52 (246/1046)

0.069

RC (%,n)

5.90 (227/3846)

6.00 (342/5696)

6.41 (67/1046)

0.617

MN2 (%,n)

18.33 (705/3846)a

19.45 (1108/5696)b

25.62 (268/1046)a, b

0.012