Fig. 3
From: Vitamin D receptor and its antiproliferative effect in human pulmonary arterial hypertension
Calcitriol exerts antiproliferative effects in human PASMC. (A) and (B) Proliferation in human PASMC from 5 (in triplicate) controls measured by BrdU incorporation and MTT assay, respectively, and (C) proliferation in PASMC from 4 different cultures from PAH-patients, in duplicate or triplicate, by MTT assay, after exposure to calcitriol (1–100 nmol/l) for 48 h. Results are expressed as mean ± SEM. *, **, *** indicates p < 0.05, p < 0.01 and p < 0.001 vs vehicle, one-way ANOVA, Bonferroni test.
