Table 2 Treatment outcome of the PDT and LEEP in the cervical HSIL.

From: Photodynamic therapy compared with loop electrosurgical excision procedure in patients with cervical high-grade squamous intraepithelial lesion

 

PDT

LEEP

p value

HPV substyle eradication rate %(n)

0.344

 Single HPV16/18

88.2 (15/17)

91.3 (21/23)

 

 Other HR-HPV

95.8 (23/24)

83.3 (20/24)

 

 HPV16 / 18 combined with other HR-HPV

90.9 (10/11)

100.0 (5/5)

 

Clearance rate of HPV infection% (n)

 3rd-6th months

76.9 (40/52)

69.2 (36/52)

0.508

 10th-12th months

88.9 (40/45)

93.5 (43/46)

0.687

 24th months

95.5 (21/22)

95.8 (23/24)

1.000

Negative conversion ratio of cytology% (n)

 3rd-6th months

89.5 (34/38)

75.0 (24/32)

0.2

 10th-12th months

97.0 (32/33)

100.0 (27/27)

1.000

 24th months

100.0 (22/22)

100.0 (24/24)

 

Cure rate at 3rd-6th months % (n)

1.000

 CR

98.1 (51/52)

98.1 (51/52)

 

 Stabilization

1.9 (1/52)

1.9 (1/52)

 

Cure rate at 10th-12th months % (n)

 CR

100.0 (45/45)

100.0 (46/46)

 

 Stabilization

0.0 (0/45)

0.0 (0/46)

 

Cure rate at 24th months % (n)

 CR

100.0 (22/22)

100.0 (24/24)

 

 Stabilization

0.0 (0/22)

0.0 (0/24)