Table 5 Univariate and multivariable analyses of prognostic factors for overall survival in patients with breast cancer (excluding patients with metastasis or other cancers).

From: Effects of antipsychotic drugs during radiotherapy in breast cancer in South Korea: a retrospective cohort study

 

Univariate analysis

Multivariable analysis

Variable

HR

95% CI

p-value

HR

95% CI

p-value

APD during RT

APD (vs. without APD)

5.55

(5.08–6.06)

< 0.0001

5.83

(5.21–6.52)

< 0.0001

Age

      

Year*

1.03

(1.03–1.03)

< 0.0001

1.02

(1.02–1.03)

< 0.0001

Hypertension

Yes (vs. No)

1.60

(1.54–1.66)

< 0.0001

1.10

(1.05–1.15)

< 0.0001

Myocardial Infarction

Yes (vs. No)

1.82

(1.58–2.1)

< 0.0001

1.25

(1.08–1.45)

0.0024

Bipolar disorder

Yes (vs. No)

1.92

(1.69–2.18)

< 0.0001

0.76

(0.66–0.88)

0.0002

Psychotic disorders

Yes (vs. No)

2.24

(1.99–2.52)

< 0.0001

0.78

(0.68–0.91)

0.0009

Depression

Yes (vs. No)

1.29

(1.23–1.36)

< 0.0001

0.98

(0.92–1.03)

0.4055

Delirium

Yes (vs. No)

3.19

(2.46–4.13)

< 0.0001

2.01

(1.54–2.61)

< 0.0001

Other psychotic disorders

Yes (vs. No)

1.24

(1.19–1.29)

< 0.0001

0.96

(0.92-1.00)

0.0716

CCI

Score*

1.16

(1.15–1.16)

< 0.0001

1.14

(1.13–1.15)

< 0.0001

  1. RT: Radiotherapy, APD: Antipsychotic drugs, CCI: Charlson comorbidity index, *Continuous value.
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