Table 2 Differences for neurohormone between patients with atrial septal defect (prior to closure) and controls. P values below 0.05 were given in bold.
From: Neurohormonal activation pattern in patients with atrial septal defect
Parameter | Atrial septal defect (n = 16) | Controls (n = 10) | P value |
|---|---|---|---|
Renin (pg/mL) | 185.0 (79.0 — 437.0) | 79.4 (60.8 — 110.0) | 0.04 |
Angiotensin II (pg/mL) | 659.0 ± 263.0 | 680.0 ± 236.0 | 0.84 |
Aldosterone (ng/dL) | 20.2 ± 7.6 | 11.7 ± 2.8 | < 0.001 |
Noradrenaline (pg/mL) | 113.0 ± 61.3 | 178.0 ± 49.4 | 0.009 |
Normetanephrine (pg/mL) | 43.8 ± 17.5 | 58.8 ± 14.9 | 0.04 |
NT pro-BNP (pg/mL) | 331.0 (242.0 — 506.0) | 69.3 (62.3 — 83.9) | < 0.001 |
Midregional ANP (pmol/L) | 246.0 (115.0 — 288.0) | 66.9 (48.8 — 82.2) | < 0.001 |
Endothelin-1 (pg/mL) | 2.93 ± 2.00 | 5.06 ± 1.25 | 0.006 |
Copeptin (pg/mL) | 43.6 ± 27.5 | 16.4 ± 8.7 | 0.002 |
