Table 3 Association of cognitive activities at ages 6, 12, and 18 years with late-life cognitive function, separate models for each age, the St. Louis Baby Tooth – Later Life Health Study, N = 4,198.

	Model 1: Activities at each age in separate models	Model 2: Activities at each age adjusted for activities at younger ages	Model 3: Simultaneous adjustment for activities at all three ages
	Age 6 activities only		Age 6 activities adjusted for age 12 and 18 activities
Age 6 activities
Quartile 1	0.0 [Reference]	N/A	0.0 [Reference]
Quartile 2	0.05 (0.01, 0.10) *		0.01 (-0.04, 0.06)
Quartile 3	0.08 (0.03, 0.12) **		0.01 (-0.04, 0.06)
Quartile 4	0.08 (0.03, 0.13) **		-0.01 (-0.07, 0.05)
	Age 12 activities only	Age 12 activities adjusted for age 6 activities	Age 12 activities adjusted for age 6 and 18 activities
Age 12 activities
Quartile 1	0.0 [Reference]	0.0 [Reference]	0.0 [Reference]
Quartile 2	0.09 (0.04, 0.14) ***	0.08 (0.03, 0.13) **	0.02 (-0.04, 0.07)
Quartile 3	0.13 (0.08, 0.18) ***	0.12 (0.07, 0.17) ***	0.00 (-0.06, 0.06)
Quartile 4	0.13 (0.07, 0.18) ***	0.11 (0.05, 0.17) ***	-0.04 (-0.11, 0.03)
	Age 18 activities only	Age 18 activities adjusted for age 6 and 12 activities	Age 18 activities adjusted for age 6 and 12 activities
Age 18 activities
Quartile 1	0.0 [Reference]	0.0 [Reference]	0.0 [Reference]
Quartile 2	0.17 (0.12, 0.22) ***	0.17 (0.11, 0.22) ***	0.17 (0.11, 0.22) ***
Quartile 3	0.19 (0.13, 0.24) ***	0.19 (0.13, 0.25) ***	0.19 (0.13, 0.25) ***
Quartile 4	0.24 (0.19, 0.29) ***	0.26 (0.19, 0.33) ***	0.26 (0.19, 0.33) ***

^a Adjusted for age, race, sex, and all socioeconomic measures (father’s education, mother’s education, childhood living arrangement and childhood family financial status, childhood home environment measures (childhood food insecurity, number of adults in the home, number of children in the home, number of bedrooms, number of people per bedroom, and whether the following amenities were shared, for family’s private use, or not present: kitchen, running hot and cold water, separate freezer, flush toilet, bathtub or shower, washing machine, clothes dryer, and number of telephones, televisions, radios, air conditioners, and cars.)
* p < 0.05, ** p < 0.01, and *** p < 0.001.

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