Table 1 Patient demographic data.

From: Trimodal therapy and surgical approaches in stage IIIA/N2 non-small cell lung cancer

Variable

T1N2

T2N2

T3N2

P-value

Number of patients

361

1055

821

 

Age (mean ± SD)

66.7 ± 12.0

68.0 ± 12.1

69.3 ± 12.7

 

Sex

   

P < .001

 

Male

209(57.9%)

724(68.6%)

657(80.0%)

 
 

Female

152(42.1%)

331(31.4%)

164(20.0%)

 

CCI score

   

P = .23

 

≦ 2

243(67.3%)

669(63.4%)

526(64.1%)

 
 

3–5

98(27.2%)

347(32.9%)

260(31.7%)

 
 

> 5

20(5.5%)

39(3.7%)

35(4.3%)

 

Cell type

   

P < .001

 

AD

284(78.7%)

585(55.5%)

303(36.9%)

 
 

SqCC

54(15.0%)

379(35.9%)

448(54.6%)

 
 

LCC

16(4.4%)

52(4.9%)

47(5.7%)

 
 

Others

7(1.9%)

39(3.7%)

23(2.8%)

 

Treatment

   

P < .001

 

None

21(5.8%)

108(10.2%)

89(10.8%)

 
 

OP alone

82(22.7%)

117(11.1%)

43(5.2%)

 
 

Neoadjuvant + OP + adjuvant

34(9.4%)

118(11.2%)

91(11.1%)

 
 

OP + adjuvant

142(39.3%)

332(31.5%)

140(17.1%)

 
 

CRT

10(2.8%)

64(6.1%)

113(13.8%)

 
 

CT ± others

39(10.8%)

174(16.5%)

198(24.1%)

 
 

Others

33(9.1%)

142(13.5%)

147(17.9%)

 

OP method

   

P < .001

 

None

105(29.1%)

490(46.5%)

548(66.8%)

 
 

Pneumonectomy/bilobectomy

4(1.1%)

36(3.4%)

31(3.8%)

 
 

Lobectomy

183(50.7%)

451(42.8%)

211(25.7%)

 
 

Sublobar resection

55(15.2%)

56(5.3%)

19(2.3%)

 
 

Unknown

14(3.9%)

22(2.1%)

12(1.5%)

 
  1. AD, adenocarcinoma; CCI, Charlson Comorbidity Index; CRT, chemoradiotherapy; CT, chemotherapy; LCC, large cell carcinoma; OP, operation; SD, standard deviation; SqCC, squamous cell carcinoma.