Table 3 Univariate and multivariate analyses of overall survival (continued).

From: Trimodal therapy and surgical approaches in stage IIIA/N2 non-small cell lung cancer

 

Univariate analysis

Multivariate analysis

Variable

HR

95% CI

P-value

HR

95% CI

P-value

Treatment

      

None (reference)

1

  

1

  

OP alone

0.228

0.184–0.282

P < .001

0.290

0.231–0.363

P < .001

Neoadjuvant + OP + adjuvant

0.193

0.155–0.240

P < .001

0.231

0.184–0.289

P < .001

OP + adjuvant

0.240

0.203–0.285

P < .001

0.308

0.256–0.371

P < .001

CRT

0.575

0.469–0.704

P < .001

0.566

0.460–0.696

P < .001

CT ± others

0.721

0.610–0.853

P < .001

0.746

0.629–0.885

P < .001

Others

0.736

0.618–0.878

P < .001

0.761

0.637–0.909

P = .003

OP method

      

None (reference)

1

  

1

  

Pneumonectomy/bilobectomy

0.351

0.261–0.472

P < .001

0.393

0.289–0.533

P < .001

Lobectomy

0.290

0.260–0.324

P < .001

0.354

0.313–0.399

P < .001

Sublobar resection

0.398

0.321–0.493

P < .001

0.534

0.427–0.668

P < .001

Unknown

0.439

0.316–0.610

P < .001

0.526

0.377–0.734

P < .001

  1. CCI, Charlson Comorbidity Index; CI, confidence interval; CRT, chemoradiotherapy; CT, chemotherapy; HR, hazard ratio; OP, operation.
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