Table 1 Results of BITOLA knowledge discovery system (top 50 drugs).

From: Exploration and practice of potential association prediction between diseases and drugs based on Swanson framework and bioinformatics

Serial number

Drug name

Frequency

Score

Serial number

Drug name

Frequency

Score

1

Heparin

687

50

26

Triiodothyronine

39

25

2

Recombinant Insulin

624

49

27

Tetrachlorodibenzodioxin

36

24

3

Enzyme Inhibitors

153

48

28

Methionine

36

23

4

Interferon Type II

138

47

29

Fish oil

36

22

5

Antilipemic Agents

102

46

30

Fatty Acids, Omega-3

33

21

6

Recombinant Cytokines

84

45

31

orlistat

30

20

7

Dexamethasone

81

44

32

Recombinant Interferon-gamma

27

19

8

Serine

81

43

33

Fenofibrate

27

18

9

Somatotropin

78

42

34

Bucladesine

27

17

10

Hypoglycemic Agents

69

41

35

Anticholesteremic Agents

27

16

11

Recombinant Interleukin-1

66

40

36

Arginine

27

15

12

Fat Emulsions, Intravenous

66

39

37

Amino Acids

27

14

13

Recombinant Interferon

66

38

38

Somatropin

24

13

14

Thiazolidinediones

60

37

39

rosiglitazone

24

12

15

Interferon Type I

60

36

40

glucagon (rDNA)

24

11

16

Glycerol

60

35

41

Recombinant Interleukin-4

24

10

17

Recombinant Interleukin-2

60

34

42

Sodium Chloride

24

9

18

Tetradecanoylphorbol Acetate

57

33

43

Tretinoin

24

8

19

Lecithin

54

32

44

Antineoplastic Agents

24

7

20

Weight Loss

54

31

45

Heparin, Low-Molecular-Weight

24

6

21

Mitochondrial uncoupling protein

48

30

46

Immune Sera

24

5

22

4-diethoxyphosphorylmethyl-N-(4-bromo-2-cyanophenyl)benzamide

48

29

47

Polyethylene Glycols

24

4

23

Interferon-alpha

42

28

48

Protamines

24

3

24

Oleic Acid

42

27

49

Adenosine Triphosphate

24

2

25

Isoproterenol

39

26

50

Forskolin

24

1

  1. Score refers to assigning scores to each drug based on their ranking. If there are 50 drugs in total, the first ranked drug will receive 50 points, and scores will be assigned sequentially. The 50th ranked drug will receive 1 point.