Table 1 Comparison of the gene sequences to produce class I lantibiotics and their homicorcin counterparts.

From: Unveiling the biosynthesis mechanism of novel lantibiotic homicorcin: an in silico analysis

Protein

Accession no.

Number of amino acids

Identity

Expect value

LanA

  

Identity with HomA

 

EciA

CAA74348

57

82%

7e-34

PepA

CAA90023

61

57%

1e-19

ElxA

AFN69432.1

56

37%

6e-07

NisA

AWJ76918.1

58

< 20%

-

LanB

  

Identity with HomB

 

EciB

CAA74350

976

83%

0.0

PepB

CAA90025.1

967

55%

0.0

ElxB

AFN69434.1

986

34%

1e-126

NisB

CAA48381.1

993

25%

1e-41

LanC

  

Identity with HomC

 

EciC

CAA74351.1

397

93%

0.0

PepC

CAA90026.1

398

58%

1e-169

ElxC

AFN69435.1

402

35%

6e-74

NisC

CAA48383.1

414

25%

2e-25

LanT1

  

Identity with HomT1

 

Epicidin 280

Not reported

-

-

-

PepT1

IPR003439

232

23%

1e-09

ElxT1

IPR003439

231

27.5%

4e-14

NisT1

IPR003439

237

25%

3e-15

LanT2

  

Identity with HomT2

 

Epicidin 280

Not reported

-

-

-

PepT2

IPR011527

277

53%

0.047

ElxT2

IPR011527

276

< 20%

-

NisT2

IPR011527

277

29%

0.041

LanP

  

Identity with HomP

 

EciP

CAA74349

300

81%

0.0

PepP

CAA90024.1

285

56%

2e-112

ElxP

AFN69433.1

311

41%

3e-68

NisP

AWJ76912.1

682

23%

8e-10

  1. LanA: structural peptide; LanB: dehydratase; LanC: cyclase; LanT1: ABC transporters; LanT2: permease; LanP: protease. Biosynthesis protein of epicidin (Eci-), Pep5 (Pep-), epilancin 15X (Elx-) and nisin A (Nis-).