Table 2 Subcellular localization of lantibiotic modification enzymes.

From: Unveiling the biosynthesis mechanism of novel lantibiotic homicorcin: an in silico analysis

Lantibiotic modification enzymes

Subcellular localization

Number of transmembrane helices

HomB

Cytoplasmic membrane side

No transmembrane helix

NisB

Cytoplasmic membrane side

No transmembrane helix

HomC

Membrane protein

3–4 transmembrane helices

NisC

Membrane protein

5 transmembrane helices

HomT1

Cytoplasm

No transmembrane helix

HomT2

Membrane protein

6 transmembrane helices

NisT

Membrane protein

6 transmembrane helices with one cytoplasmic domain

HomP

Cell wall

1 transmembrane helix in C-terminal region

NisP

Cell wall

1 transmembrane helix in C-terminal region