Fig. 5

Presepsin is secreted in the kidney interstitium. (a) Immunofluorescence staining of presepsin. The kidney interstitium was immunostained with presepsin (green). Nuclei were counterstained with DAPI (blue). Scale bar, 50 μm. (b) Correlation analysis between urinary presepsin/creatinine levels and presepsin fluorescent staining area. We randomly selected four cases from each of the four categories of interstitial inflammation cell infiltration severity (n = 16); the average value of the presepsin fluorescent staining area for each case is presented. Values were calculated using Spearman’s correlation coefficient test. DAPI, 4’,6-diamidino-2-phenylindole.