Table 1 Clinical profile of participating subjects with Hashimoto’s disease.

From: Preliminary investigations of plasma lipidome and selenium levels in adults with treated hypothyroidism and in healthy individuals without selenium deficiency

Variable

Hashimoto’s disease

Valid N

Mean

Median

Minimum

Maximum

Lower quartile

Upper quartile

Quartile range

Std. dev

Age (years)

24

33.500

29.500

22.000

59.000

23.000

43.000

20.00

11.527

BMI (kg/m2)

24

23.865

23.420

17.710

35.010

20.660

26.730

6.070

4.346

LT4 dose (µg)

24

75.682

75.000

12.500

137.000

56.250

100.000

43.750

30.362

Hypothyroidism (years)

24

5.750

5.000

1.000

19.000

2.500

8.000

5.500

4.406

TSH (uIU/mL)

24

1.989

1.910

0.870

3.795

1.550

2.380

0.830

0.722

fT4 (ng/dL)

24

1.180

1.100

0.810

1.710

0.970

1.410

0.440

0.269

fT3 (pg/mL)

24

2.983

2.985

2.040

4.650

2.445

3.415

0.970

0.6360

Total cholesterol (mg/dL)

24

173.741

175.500

98.000

245.000

158.500

188.500

30.000

31.957

HDL cholesterol (mg/dL)

24

62.715

63.500

39.000

98.000

55.200

68.500

13.300

14.062

LDL cholesterol (mg/dL)

24

92.081

92.600

49.000

147.200

67.900

105.800

37.900

25.080

Triglycerides (mg/dL)

24

89.226

96.000

36.000

142.000

61.500

114.000

52.500

31.058

AIP

24

0.135

0.149

-0.142

0.430

0.004

0.289

0.280

0.171

Fasting glucose (mg/dL)

24

88.271

89.000

77.000

98.000

83.500

92.000

8.500

5.651

Fasting insulin (mIU/L)

24

8.313

9.300

3.000

12.000

5.960

10.300

4.340

2.583

HOMA-IR

24

1.821

1.962

0.578

2.667

1.354

2.347

0.993

0.591

Se (µg/L)

24

89.993

93.805

53.660

122.200

76.300

101.700

25.400

20.251

Lipid species

lysoPC a C14:0

24

2.111

1.970

1.120

4.110

1.575

2.310

0.735

0.755

lysoPC a C16:0

24

126.458

127.000

88.800

174.000

113.500

137.000

23.500

21.833

lysoPC a C16:1

24

2.940

2.885

1.760

4.810

2.430

3.305

0.875

0.708

lysoPC a C17:0

24

2.083

2.095

0.853

3.360

1.775

2.435

0.660

0.557

lysoPC a C18:0

24

39.338

39.150

19.700

53.800

34.700

46.500

11.800

8.537

lysoPC a C18:1

24

29.242

30.000

13.200

39.500

25.250

34.600

9.350

6.854

lysoPC a C18:2

24

40.404

39.600

12.000

66.400

30.850

51.250

20.400

13.928

lysoPC a C20:3

24

2.545

2.565

1.440

3.560

2.200

2.940

0.740

0.594

lysoPC a C20:4

24

7.774

7.425

3.790

11.900

6.350

9.050

2.700

2.173

lysoPC a C24:0

24

0.214

0.201

0.086

0.576

0.156

0.246

0.090

0.099

lysoPC a C26:0

24

0.332

0.233

0.134

1.330

0.188

0.381

0.193

0.255

lysoPC a C26:1

24

0.216

0.153

0.088

0.886

0.123

0.236

0.112

0.171

lysoPC a C28:0

24

0.299

0.247

0.144

0.955

0.200

0.332

0.132

0.169

lysoPC a C28:1

24

0.431

0.403

0.186

1.220

0.296

0.503

0.207

0.217

PC aa C24:0

24

50.577

50.692

0.083

101.000

0.138

101.000

100.862

51.507

PC aa C26:0

24

80.237

101.000

0.841

101.000

101.000

101.000

0.000

41.345

PC aa C28:1

24

2.727

2.845

1.480

3.870

2.170

3.180

1.0100

0.755

PC aa C30:0

24

3.775

3.680

1.860

10.300

2.820

4.220

1.40

1.801

PC aa C30:2

24

101.000

101.000

101.000

101.000

101.000

101.000

0.000

0.000

PC aa C32:0

24

12.525

12.150

7.700

25.800

10.200

14.050

3.850

3.644

PC aa C32:1

24

13.434

11.550

5.460

43.600

8.610

15.800

7.190

7.953

PC aa C32:2

24

2.854

2.735

0.966

5.900

1.960

3.425

1.465

1.236

PC aa C32:3

24

0.353

0.366

0.203

0.534

0.286

0.413

0.127

0.085

PC aa C34:1

24

207.667

198.000

116.000

457.000

171.500

220.500

49.000

64.836

PC aa C34:2

24

426.958

416.000

258.000

668.000

348.500

484.000

135.500

95.442

PC aa C34:3

24

13.174

12.450

7.310

23.600

11.000

14.750

3.7500

3.901

PC aa C34:4

24

1.428

1.330

0.489

3.650

0.978

1.555

0.5770

0.726

PC aa C36:0

24

1.087

1.075

0.198

2.060

0.765

1.450

0.6850

0.519

PC aa C36:1

24

39.442

38.200

24.200

82.200

31.700

44.050

12.350

12.060

PC aa C36:2

24

212.833

215.500

127.000

280.000

169.000

256.500

87.500

48.007

PC aa C36:3

24

105.892

100.650

59.700

167.000

87.600

111.500

23.900

27.680

PC aa C36:4

24

168.125

158.500

87.000

316.000

141.500

174.500

33.000

49.408

PC aa C36:5

24

18.322

16.950

7.750

59.200

13.150

21.500

8.350

10.006

PC aa C36:6

24

0.664

0.679

0.242

1.730

0.500

0.772

0.2720

0.2911

PC aa C38:0

24

2.366

2.200

1.540

3.750

1.825

2.780

0.955

0.693

PC aa C38:1

24

0.511

0.526

0.195

1.010

0.343

0.641

0.2980

0.205

PC aa C38:3

24

31.929

30.500

22.000

60.800

26.900

34.300

7.40

8.316

PC aa C38:4

24

78.104

74.350

49.200

146.000

64.650

86.600

21.950

20.336

PC aa C38:5

24

36.438

34.900

20.800

85.400

32.750

37.950

5.200

11.530

PC aa C38:6

24

64.133

59.150

29.900

140.000

46.800

71.200

24.400

23.620

PC aa C40:1

24

96.807

101.000

0.371

101.000

101.000

101.000

0.000

20.540

PC aa C40:2

24

0.173

0.174

0.096

0.264

0.148

0.192

0.044

0.039

PC aa C40:3

24

0.324

0.306

0.237

0.470

0.259

0.364

0.104

0.075

PC aa C40:4

24

1.893

1.795

0.955

4.520

1.480

2.105

0.625

0.6561

PC aa C40:5

24

5.324

4.900

3.380

16.900

4.255

5.445

1.190

2.5760

PC aa C40:6

24

18.375

16.400

10.800

52.000

13.500

19.550

6.050

8.589

PC aa C42:0

24

0.365

0.319

0.201

0.648

0.297

0.434

0.136

0.116

PC aa C42:1

24

0.172

0.166

0.090

0.289

0.121

0.216

0.094

0.055

PC aa C42:2

24

0.138

0.135

0.075

0.195

0.108

0.169

0.061

0.035

PC aa C42:4

24

0.105

0.105

0.063

0.167

0.095

0.119

0.025

0.025

PC aa C42:5

24

0.207

0.202

0.112

0.403

0.165

0.232

0.066

0.060

PC aa C42:6

24

0.236

0.227

0.146

0.444

0.201

0.260

0.059

0.063

PC ae C30:0

24

0.367

0.363

0.157

0.548

0.305

0.425

0.120

0.095

PC ae C30:1

24

71.574

101.000

0.016

101.000

0.243

101.000

100.757

46.842

PC ae C30:2

24

0.084

0.079

0.043

0.173

0.065

0.100

0.0355

0.029

PC ae C32:1

24

2.493

2.365

1.520

3.930

2.040

2.905

0.8650

0.597

PC ae C32:2

24

0.600

0.602

0.346

0.840

0.477

0.719

0.242

0.147

PC ae C34:0

24

1.086

1.030

0.523

2.070

0.909

1.175

0.260

0.321

PC ae C34:1

24

8.873

8.605

5.700

11.500

7.950

10.300

2.350

1.628

PC ae C34:2

24

11.637

12.050

5.840

17.300

8.650

13.850

5.200

3.243

PC ae C34:3

24

7.165

7.200

4.600

10.700

5.530

8.165

2.635

1.835

PC ae C36:0

24

0.561

0.583

0.380

0.806

0.451

0.664

0.213

0.122

PC ae C36:1

24

5.924

5.930

3.440

8.360

4.750

6.710

1.960

1.252

PC ae C36:2

24

11.070

11.200

6.530

16.100

8.875

13.100

4.225

2.584

PC ae C36:3

24

6.450

6.365

3.850

9.770

4.825

7.630

2.805

1.792

PC ae C36:4

24

16.777

17.000

7.240

28.800

12.300

20.300

8.000

5.047

PC ae C36:5

24

10.198

9.750

5.410

16.300

7.950

12.900

4.950

2.868

PC ae C38:0

24

1.422

1.370

0.854

2.370

1.240

1.615

0.375

0.323

PC ae C38:1

24

25.376

0.185

0.015

101.000

0.111

50.698

50.587

44.600

PC ae C38:2

24

1.011

1.000

0.611

1.580

0.870

1.120

0.250

0.2441

PC ae C38:3

24

2.414

2.390

1.500

3.340

2.160

2.740

0.580

0.474

PC ae C38:4

24

9.718

9.270

6.020

16.300

8.355

11.050

2.695

2.396

PC ae C38:5

24

14.589

15.050

9.940

22.500

11.250

17.500

6.250

3.424

PC ae C38:6

24

6.080

6.005

2.990

9.270

4.760

7.265

2.5050

1.673

PC ae C40:1

24

0.831

0.815

0.558

1.340

0.703

0.930

0.22

0.185

PC ae C40:2

24

1.242

1.215

0.632

1.810

0.933

1.455

0.522

0.33

PC ae C40:3

24

0.619

0.587

0.403

0.889

0.553

0.670

0.116

0.121

PC ae C40:4

24

1.454

1.385

0.859

2.540

1.300

1.555

0.255

0.364

PC ae C40:5

24

2.186

2.095

1.430

3.360

1.925

2.370

0.445

0.463

PC ae C40:6

24

2.983

2.880

1.880

4.860

2.435

3.375

0.940

0.760

PC ae C42:0

24

75.868

101.000

0.396

101.000

50.782

101.000

50.218

44.466

PC ae C42:1

24

0.185

0.184

0.118

0.272

0.158

0.214

0.055

0.040

PC ae C42:2

24

0.337

0.314

0.235

0.570

0.285

0.374

0.089

0.080

PC ae C42:3

24

0.479

0.473

0.222

0.691

0.413

0.578

0.165

0.116

PC ae C42:4

24

8.947

0.549

0.346

101.000

0.506

0.710

0.204

28.352

PC ae C42:5

24

1.492

1.365

0.874

2.580

1.255

1.695

0.440

0.407

PC ae C44:3

24

0.066

0.065

0.035

0.103

0.053

0.077

0.024

0.018

PC ae C44:4

24

0.244

0.220

0.114

0.421

0.208

0.282

0.074

0.072

PC ae C44:5

24

1.300

1.230

0.694

2.380

1.090

1.435

0.345

0.376

PC ae C44:6

24

0.789

0.748

0.423

1.460

0.658

0.863

0.205

0.251

SM (OH) C14:1

24

4.746

4.575

2.720

7.070

3.725

5.975

2.250

1.308

SM (OH) C16:1

24

2.448

2.410

1.410

3.790

2.050

2.830

0.780

0.661

SM (OH) C22:1

24

7.929

7.840

5.000

11.000

6.690

9.035

2.345

1.741

SM (OH) C22:2

24

7.336

7.105

5.040

10.400

5.825

9.050

3.225

1.647

SM (OH) C24:1

24

0.740

0.721

0.450

1.110

0.605

0.836

0.2305

0.178

SM C16:0

24

97.396

94.750

64.900

130.000

84.250

112.500

28.25

17.964

SM C16:1

24

12.260

11.750

8.090

17.100

9.635

14.650

5.015

2.7261

SM C18:0

24

17.160

16.600

9.540

24.300

14.250

20.550

6.300

4.2460

SM C18:1

24

7.770

7.410

4.550

11.300

6.305

9.125

2.820

1.8818

SM C20:2

24

0.205

0.178

0.069

0.376

0.140

0.266

0.126

0.0894

SM C22:3

24

101.000

101.000

101.000

101.000

101.000

101.000

0.000

0.0000

SM C24:0

24

12.099

11.750

8.220

20.500

10.450

13.600

3.150

2.591

SM C24:1

24

39.229

39.950

26.000

61.600

33.150

44.550

11.400

7.856

SM C26:0

24

0.088

0.089

0.016

0.141

0.065

0.109

0.044

0.029

SM C26:1

24

0.234

0.233

0.105

0.373

0.178

0.280

0.102

0.067

  1. Abbreviations of lipid species: Lysophosphatidylcholine with acyl residue (lysoPC a); Phosphatidylcholine with diacyl residue (PC aa); Phosphatidylcholine with acyl-alkyl residue (PC ae); Hydroxysphingomyelin with acyl residue (SM (OH)); Sphingomyelin with acyl residue (SM).
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