Table 2 Clinical profile of participating subjects with non-autoimmune hypothyroidism.

From: Preliminary investigations of plasma lipidome and selenium levels in adults with treated hypothyroidism and in healthy individuals without selenium deficiency

Variable

Non-autoimmune hypothyroidism (Hypo-no-Hashimoto)

Valid N

Mean

Median

Minimum

Maximum

Lower quartile

Upper quartile

Quartile range

Std. dev

Age (years)

11

29.273

24.000

21.000

43.000

22.000

38.000

16.000

8.343

BMI (kg/m2)

11

23.072

24.510

19.000

25.820

19.840

25.350

5.510

2.711

LT4 dose (µg)

11

47.074

50.000

25.000

75.000

28.570

57.140

28.570

16.290

Hypothyroidism (years)

11

4.000

2.000

1.000

12.000

1.000

8.000

7.000

4.242

TSH (uIU/mL)

11

1.663

1.680

0.704

2.674

1.140

2.230

1.090

0.590

fT4 (ng/dL)

11

2.071

1.320

0.850

9.930

1.190

1.520

0.330

2.614

fT3 (pg/mL)

11

3.175

2.980

2.410

4.050

2.730

3.730

1.000

0.583

Total cholesterol (mg/dL)

11

164.273

164.000

134.000

202.000

152.000

174.000

22.000

18.810

HDL cholesterol (mg/dL)

11

58.182

57.000

48.000

89.000

49.000

59.000

10.000

12.015

LDL cholesterol (mg/dL)

11

90.900

92.500

69.600

134.000

73.000

97.200

24.200

18.397

Triglycerides (mg/dL)

11

87.000

89.000

36.000

123.000

70.000

105.000

35.000

24.157

AIP

11

0.163

0.225

-0.393

0.400

0.089

0.265

0.176

0.205

Fasting glucose (mg/dL)

11

88.091

86.000

80.000

101.000

82.000

93.000

11.000

6.876

Fasting insulin (mIU/L)

11

8.120

7.600

4.600

10.920

6.400

9.830

3.430

2.058

HOMA-IR

11

1.769

1.558

1.034

2.508

1.422

2.230

0.807

0.489

Se (µg/L)

11

84.593

82.500

45.550

126.667

57.917

100.250

42.333

27.545

Lipid species

lysoPC a C14:0

11

1.782

1.540

1.020

3.180

1.290

2.170

0.880

0.705

lysoPC a C16:0

11

110.064

106.000

79.300

149.000

98.200

122.000

23.800

18.653

lysoPC a C16:1

11

2.618

2.450

1.780

4.920

1.960

3.020

1.060

0.886

lysoPC a C17:0

11

1.894

1.850

1.420

2.640

1.500

2.260

0.760

0.411

lysoPC a C18:0

11

33.227

35.800

18.500

44.900

25.800

39.300

13.500

8.256

lysoPC a C18:1

11

24.682

23.900

17.400

31.600

18.900

30.200

11.300

5.224

lysoPC a C18:2

11

31.736

31.600

13.900

50.000

28.000

38.200

10.200

10.055

lysoPC a C20:3

11

2.028

1.830

1.050

4.280

1.390

2.520

1.130

0.883

lysoPC a C20:4

11

6.275

5.950

3.850

8.740

4.840

8.230

3.390

1.833

lysoPC a C24:0

11

0.258

0.216

0.127

0.493

0.202

0.321

0.119

0.106

lysoPC a C26:0

11

0.414

0.404

0.128

0.822

0.212

0.653

0.441

0.235

lysoPC a C26:1

11

0.239

0.177

0.097

0.541

0.139

0.392

0.253

0.140

lysoPC a C28:0

11

0.323

0.295

0.166

0.652

0.218

0.364

0.146

0.141

lysoPC a C28:1

11

0.500

0.476

0.202

0.915

0.327

0.618

0.291

0.216

PC aa C24:0

11

36.811

0.142

0.076

101.000

0.124

101.000

100.876

50.890

PC aa C26:0

11

46.407

1.110

0.849

101.000

0.874

101.000

100.126

52.268

PC aa C28:1

11

2.611

2.600

1.990

4.120

2.060

2.970

0.910

0.619

PC aa C30:0

11

3.177

3.320

1.860

4.610

2.200

4.400

2.200

1.064

PC aa C30:2

11

101.000

101.000

101.000

101.000

101.000

101.000

0.000

0.000

PC aa C32:0

11

11.278

10.800

8.960

16.900

9.260

12.700

3.440

2.386

PC aa C32:1

11

11.562

11.200

4.920

23.800

7.860

13.300

5.440

5.405

PC aa C32:2

11

2.454

2.100

0.370

5.470

1.660

3.690

2.030

1.413

PC aa C32:3

11

0.330

0.305

0.203

0.553

0.238

0.442

0.204

0.115

PC aa C34:1

11

186.182

176.000

140.000

246.000

161.000

215.000

54.000

35.439

PC aa C34:2

11

383.091

375.000

321.000

485.000

356.000

404.000

48.000

43.532

PC aa C34:3

11

12.804

11.400

5.440

24.300

10.200

15.600

5.400

5.112

PC aa C34:4

11

1.179

0.947

0.343

2.410

0.818

1.750

0.932

0.650

PC aa C36:0

11

0.950

0.810

0.125

2.100

0.721

1.340

0.619

0.535

PC aa C36:1

11

34.600

35.200

27.200

43.500

28.100

38.900

10.800

5.939

PC aa C36:2

11

190.364

183.000

158.000

255.000

171.000

201.000

30.000

27.990

PC aa C36:3

11

96.245

88.700

66.400

124.000

85.800

111.000

25.200

16.881

PC aa C36:4

11

144.482

151.000

99.300

184.000

111.000

168.000

57.000

29.848

PC aa C36:5

11

18.834

16.800

9.370

33.900

13.200

24.100

10.900

7.238

PC aa C36:6

11

0.632

0.505

0.306

1.210

0.416

0.842

0.426

0.270

PC aa C38:0

11

2.074

2.000

1.460

3.140

1.670

2.230

0.560

0.557

PC aa C38:1

11

9.762

0.622

0.169

101.000

0.364

1.010

0.646

30.261

PC aa C38:3

11

28.336

25.500

18.200

41.500

23.100

37.600

14.500

7.390

PC aa C38:4

11

68.173

61.400

44.100

104.000

55.600

75.700

20.100

17.763

PC aa C38:5

11

34.509

34.200

23.700

51.000

26.500

40.800

14.300

7.814

PC aa C38:6

11

67.091

61.500

45.800

123.000

50.800

72.800

22.000

21.921

PC aa C40:1

11

91.854

101.000

0.391

101.000

101.000

101.000

0.000

30.334

PC aa C40:2

11

0.171

0.170

0.096

0.257

0.144

0.193

0.049

0.042

PC aa C40:3

11

0.319

0.309

0.224

0.448

0.270

0.348

0.078

0.063

PC aa C40:4

11

1.583

1.530

0.967

2.670

1.100

1.880

0.780

0.520

PC aa C40:5

11

4.902

4.220

2.800

9.340

3.810

5.760

1.950

1.809

PC aa C40:6

11

18.282

17.200

12.800

29.200

13.000

23.200

10.200

5.473

PC aa C42:0

11

0.364

0.328

0.252

0.703

0.306

0.379

0.073

0.119

PC aa C42:1

11

0.179

0.172

0.104

0.311

0.161

0.183

0.022

0.053

PC aa C42:2

11

0.139

0.131

0.106

0.198

0.112

0.165

0.053

0.028

PC aa C42:4

11

0.096

0.096

0.057

0.138

0.066

0.130

0.064

0.030

PC aa C42:5

11

0.214

0.206

0.148

0.366

0.155

0.247

0.092

0.068

PC aa C42:6

11

0.230

0.225

0.113

0.334

0.172

0.291

0.119

0.066

PC ae C30:0

11

0.334

0.311

0.207

0.475

0.251

0.412

0.161

0.092

PC ae C30:1

11

55.114

101.000

0.021

101.000

0.062

101.000

100.938

52.718

PC ae C30:2

11

0.084

0.085

0.051

0.118

0.067

0.099

0.032

0.018

PC ae C32:1

11

2.131

2.230

1.500

2.950

1.580

2.410

0.830

0.466

PC ae C32:2

11

0.532

0.507

0.452

0.737

0.454

0.592

0.138

0.090

PC ae C34:0

11

0.923

0.799

0.652

1.430

0.700

1.100

0.400

0.252

PC ae C34:1

11

8.244

7.730

5.710

11.400

6.590

9.860

3.270

1.917

PC ae C34:2

11

9.494

8.900

5.520

12.900

8.160

11.800

3.640

2.236

PC ae C34:3

11

6.322

5.490

4.210

11.200

4.960

7.350

2.390

1.988

PC ae C36:0

11

0.540

0.483

0.387

0.951

0.411

0.586

0.175

0.161

PC ae C36:1

11

5.577

5.680

3.850

7.570

4.220

7.010

2.790

1.350

PC ae C36:2

11

9.991

10.100

7.160

12.600

7.780

11.400

3.620

1.963

PC ae C36:3

11

5.029

4.740

3.070

6.630

4.350

6.210

1.860

1.082

PC ae C36:4

11

12.189

11.700

7.530

16.900

9.620

14.500

4.880

3.017

PC ae C36:5

11

8.080

7.530

5.170

14.600

5.990

9.470

3.480

2.718

PC ae C38:0

11

1.466

1.510

0.983

2.080

1.220

1.780

0.560

0.347

PC ae C38:1

11

36.861

0.276

0.068

101.000

0.171

101.000

100.829

50.850

PC ae C38:2

11

0.879

0.916

0.434

1.280

0.667

1.090

0.423

0.260

PC ae C38:3

11

2.224

2.300

1.060

3.010

1.910

2.690

0.780

0.583

PC ae C38:4

11

8.051

7.650

4.480

10.800

6.450

10.100

3.650

2.042

PC ae C38:5

11

11.657

11.500

8.610

16.700

9.390

13.500

4.110

2.553

PC ae C38:6

11

5.242

5.000

4.030

7.840

4.090

5.710

1.620

1.290

PC ae C40:1

11

0.779

0.717

0.550

1.160

0.670

0.890

0.220

0.173

PC ae C40:2

11

1.203

1.190

0.819

1.640

0.924

1.450

0.526

0.274

PC ae C40:3

11

0.588

0.575

0.412

0.781

0.460

0.730

0.270

0.129

PC ae C40:4

11

1.280

1.310

0.794

1.800

1.070

1.490

0.420

0.299

PC ae C40:5

11

1.946

1.880

1.390

3.060

1.480

2.340

0.860

0.517

PC ae C40:6

11

2.882

2.790

1.990

4.460

2.460

2.800

0.340

0.759

PC ae C42:0

11

55.321

101.000

0.388

101.000

0.473

101.000

100.527

52.480

PC ae C42:1

11

0.185

0.184

0.121

0.263

0.150

0.219

0.069

0.044

PC ae C42:2

11

0.336

0.321

0.246

0.558

0.290

0.340

0.050

0.082

PC ae C42:3

11

0.464

0.447

0.314

0.722

0.416

0.471

0.055

0.106

PC ae C42:4

11

0.526

0.517

0.335

0.724

0.443

0.604

0.161

0.123

PC ae C42:5

11

1.403

1.420

0.922

2.090

1.100

1.720

0.620

0.364

PC ae C44:3

11

0.074

0.073

0.042

0.111

0.048

0.096

0.048

0.024

PC ae C44:4

11

0.241

0.242

0.148

0.324

0.196

0.286

0.090

0.055

PC ae C44:5

11

1.247

1.220

0.526

1.980

0.919

1.570

0.651

0.434

PC ae C44:6

11

0.800

0.775

0.542

1.340

0.610

0.936

0.326

0.222

SM (OH) C14:1

11

4.487

4.140

2.970

6.940

3.710

5.590

1.880

1.236

SM (OH) C16:1

11

2.266

2.150

1.510

3.430

1.780

2.780

1.000

0.602

SM (OH) C22:1

11

7.995

7.380

5.200

15.000

6.270

8.840

2.570

2.681

SM (OH) C22:2

11

7.055

6.550

4.670

10.900

5.490

8.670

3.180

1.945

SM (OH) C24:1

11

0.711

0.665

0.419

1.320

0.559

0.824

0.265

0.242

SM C16:0

11

89.909

86.700

75.900

115.000

80.100

99.300

19.200

12.564

SM C16:1

11

11.305

10.600

9.020

15.100

9.920

12.600

2.680

1.853

SM C18:0

11

15.518

15.400

11.300

18.900

13.800

18.500

4.700

2.487

SM C18:1

11

6.884

6.800

4.470

8.980

5.990

7.770

1.780

1.382

SM C20:2

11

0.194

0.197

0.117

0.249

0.169

0.240

0.071

0.045

SM C22:3

11

101.000

101.000

101.000

101.000

101.000

101.000

0.000

0.000

SM C24:0

11

11.670

12.100

8.100

17.400

9.650

13.000

3.350

2.601

SM C24:1

11

36.964

36.100

28.700

45.100

32.100

43.000

10.900

5.440

SM C26:0

11

0.089

0.083

0.039

0.153

0.062

0.117

0.055

0.035

SM C26:1

11

0.229

0.212

0.132

0.421

0.171

0.262

0.091

0.081

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