Table 1 Thermodynamic parameters of pyrocatechol interaction with 5FU, CPT11, LV and CTX at room temperature.

From: EGFR-targeting polydopamine nanoparticles co-loaded with 5-fluorouracil, irinotecan, and leucovorin to potentially enhance metastatic colorectal cancer therapy

 

Ka (M− 1)

ΔH° (kJ/mol)

ΔG° (kJ/mol)

ΔS° (J/mol K)

5FU

1620

-2.7

-18.34

52.5

CPT11

1020

-6.7

-17.2

35.1

LV

5110

-15.8

-21.2

18.1

CTX

6940

-4.8

-21.9

57.4

Back to article page