Fig. 4 | Scientific Reports

Fig. 4

From: Metformin-loaded nanoparticles reduce hyperglycemia-associated oxidative stress and induce eNOS phosphorylation in vascular endothelial cells

Fig. 4

Effect of nanoMIL-89 and MET@nanoMIL-89 on ROS levels, measured by DHE fluorescence intensity, in HUVECs cultured in hyperglycemic media. Data are presented as mean ± SEM for n = 3. Statistical analysis comparing effects between different groups was conducted using two-way ANOVA, followed by Bonferroni post-tests, with #p < 0.05 considered significant. Each group was compared to the control using one-way ANOVA, followed by Dunnett’s Multiple Comparison Tests, where *p < 0.05 was considered significant.

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