Fig. 5 | Scientific Reports

Fig. 5

From: Metformin-loaded nanoparticles reduce hyperglycemia-associated oxidative stress and induce eNOS phosphorylation in vascular endothelial cells

Fig. 5

Effect of nanoMIL-89 and MET@nanoMIL-89 on (A) Phosphorylated eNOS and (B) Total eNOS, (C) Phosphorylated AKT, and (D) total AKT expression in HUVECs treated under hyperglycemic conditions. Data are presented as mean ± SEM for n = 3. Statistical analysis using one-way ANOVA, followed by Dunnett’s Multiple Comparison Tests, was performed to compare the effects of each condition to the relevant control, with *p < 0.05 considered significant.

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