Table 4 Association between SII and risk of 30-days all-cause mortality.

From: High level of systemic immune inflammation index elevates delirium risk among patients in intensive care unit

Variates

Univariable COX regression

Multivariable COX regression

HR (95% CI)

p

HR (95% CI)

p

SII >  = 1406.07

1.44(1.23,1.69)

 < 0.001

1.35(1.10,1.65)

0.005

Age grade

0.93(0.81,1.06)

0.273

  

Gender

0.87(0.75,1.02)

0.078

  

Heart rate

1.02(1.01,1.02)

 < 0.001

1.01(1.00,1.01)

0.086

Respiratory rate

1.07(1.05,1.09)

 < 0.001

1.03(1.01,1.06)

0.012

SBP

0.99(0.99,1.00)

0.001

1.00(1.00,1.01)

0.618

DBP

1.00(0.99,1.00)

0.441

  

Temperature

0.91(0.76,1.08)

0.277

  

SpO2

0.92(0.89,0.96)

0.000

1.00(1.00,1.00)

0.975

Glucose

1.00(1.00,1.00)

0.059

  

Hemoglobin

1.01(0.98,1.05)

0.413

  

Creatinine

1.01(0.97,1.05)

0.755

  

Albumin

0.97(0.96,0.98)

 < 0.001

0.99(0.97,1.01)

0.375

Bicarbonate

0.96(0.95,0.98)

 < 0.001

1.00(1.00,1.00)

0.091

Calcium

0.86(0.79,0.94)

0.001

0.97(0.86,1.10)

0.634

Chloride

0.98(0.97,0.99)

0.003

1.00(0.98,1.01)

0.712

Potassium

0.95(0.84,1.07)

0.410

  

PT

1.01(1.01,1.01)

 < 0.001

1.01(1.00,1.01)

0.013

PTT

1.01(1.00,1.01)

 < 0.001

1.00(1.00,1.00)

0.783

ALT

1.00(1.00,1.00)

0.089

  

AST

1.00(1.00,1.00)

 < 0.001

1.00(1.00,1.00)

0.918

Bilirubin

1.04(1.02,1.05)

 < 0.001

1.00(1.00,1.00)

0.019

DM

0.76(0.64,0.9)

0.001

0.72(0.57,0.90)

0.005

CKD

0.85(0.72,1.00)

0.054

  

COPD

0.98(0.80,1.19)

0.803

  

SOFA

1.11(1.10,1.13)

 < 0.001

1.01(1.00,1.01)

 < 0.001

CCI

1.03(1.01,1.06)

0.019

1.06(1.02,1.10)

0.002

  1. SII systemic immune-inflammation index, HR hazard ratio, SBP systolic blood pressure, DBP diastolic blood, SpO2 saturation of the pulse oxygen, PT prothrombin time, PTT partial thromboplastin time, ALT alanine aminotransferase, AST aspartate aminotransferase, DM diabetes mellitus, CKD chronic kidney disease, COPD chronic obstructive pulmonary disease; pressure, SOFA sequential organ failure assessment, CCI Charlson comorbidity index.
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